Abstract
A total of 131 isolates of Fusarium poae and F. sporotrichioides from overwintered cereals, which were associated with the alimentary toxic aleukia toxicoses in the Soviet Union, were tested for their ability to produce T-2 toxin [4 beta, 15 diacetoxy-8alpha-(3-methylbutyryloxy)-12,13-epoxytrichothec-9-en 3alpha-ol]. The presence of T-2 toxin was determined by thin-layer chromatography, gas-liquid chromatography, spectroscopic analyses, and the rabbit skin test. A good correlation was demonstrated between T-2 toxin dectetion by thin-layer chromatography and inflammatory skin reactions of rabbits.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bamburg J. R., Riggs N. V., Strong F. M. The structures of toxins from two strains of Fusarium tricinctum. Tetrahedron. 1968 Apr;24(8):3329–3336. doi: 10.1016/s0040-4020(01)92631-6. [DOI] [PubMed] [Google Scholar]
- Burmeister H. R., Ellis J. J., Hesseltine C. W. Survey for fusaria that elaborate T-2 toxin. Appl Microbiol. 1972 Jun;23(6):1165–1166. doi: 10.1128/am.23.6.1165-1166.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Eppley R. M., Stoloff L., Trucksess M. W., Chung C. W. Survey of corn for Fusarium toxins. J Assoc Off Anal Chem. 1974 May;57(3):632–635. [PubMed] [Google Scholar]
- Gilgan M. W., Smalley E. B., Strong F. M. Isolation and partial characterization of a toxin from Fusarium tricinctum on moldy corn. Arch Biochem Biophys. 1966 Apr;114(1):1–3. doi: 10.1016/0003-9861(66)90297-9. [DOI] [PubMed] [Google Scholar]
- Hsu I. C., Smalley E. B., Strong F. M., Ribelin W. E. Identification of T-2 toxin in moldy corn associated with a lethal toxicosis in dairy cattle. Appl Microbiol. 1972 Nov;24(5):684–690. doi: 10.1128/am.24.5.684-690.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Joffe A. Z. A modern system of Fusarium taxonomy. Mycopathol Mycol Appl. 1974 Aug 30;53(1):201–228. doi: 10.1007/BF02127209. [DOI] [PubMed] [Google Scholar]
- Joffe A. Z. Growth and toxigenicity of Fusaria of the Sporotrichiella section as related to environmental factors and culture substrates. Mycopathol Mycol Appl. 1974 Oct 15;54(1):35–46. doi: 10.1007/BF02055971. [DOI] [PubMed] [Google Scholar]
- Joffe A. Z., Palti J. Relations between harmful effects on plants and on animals of toxins produced by species of Fusarium. Mycopathol Mycol Appl. 1974 Apr 30;52(3):209–218. doi: 10.1007/BF02198745. [DOI] [PubMed] [Google Scholar]
- Joffe A. Z., Palti J. Taxonomic study of fusaria of the sporotrichiella section used in recent toxicological work. Appl Microbiol. 1975 May;29(5):575–579. doi: 10.1128/am.29.5.575-579.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Keyl A. C., Lewis J. C., Ellis J. J., Yates S. G., Tookey H. L. Toxic fungi isolated from tall fescue. Mycopathol Mycol Appl. 1967 Apr 28;31(3):327–331. doi: 10.1007/BF02053433. [DOI] [PubMed] [Google Scholar]
- Marasas W. F., Bamburg J. R., Smalley E. B., Strong F. M., Ragland W. L., Degurse P. E. Toxic effects on trout, rats, and mice of T-2 toxin produced by the fungus Fusarium tricinctum (Cd.) Snyd. et Hans. Toxicol Appl Pharmacol. 1969 Sep;15(2):471–482. doi: 10.1016/0041-008x(69)90045-3. [DOI] [PubMed] [Google Scholar]
- Mirocha C. J., Pathre S. Identification of the toxic principle in a sample of poaefusarin. Appl Microbiol. 1973 Nov;26(5):719–724. doi: 10.1128/am.26.5.719-724.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Schoental R., Joffe A. Z. Lesions induced in rodents by extracts from cultures of Fusarium poae and F. sporotrichioides. J Pathol. 1974 Jan;112(1):37–42. doi: 10.1002/path.1711120108. [DOI] [PubMed] [Google Scholar]
- Smalley E. B. T-2 toxin. J Am Vet Med Assoc. 1973 Dec 1;163(11):1278–1281. [PubMed] [Google Scholar]
- Ueno Y., Ishikawa Y., Amakai K., Nakajima M., Saito M. Comparative study on skin-necrotizing effect of scirpene metabolites of Fusaria. Jpn J Exp Med. 1970 Feb;40(1):33–38. [PubMed] [Google Scholar]
- Ueno Y., Ishikawa Y., Nakajima M., Sakai K., Ishii K. Toxicological approaches to the metabolites of Fusaria. I. Screening of toxic strains. Jpn J Exp Med. 1971 Aug;41(4):257–272. [PubMed] [Google Scholar]
- Ueno Y., Sato N., Ishii K., Sakai K., Enomoto M. Toxicological approaches to the metabolites of Fusaria. V. Neosolaniol, T-2 toxin and butenolide, toxic metabolites of Fusarium sporotrichioides NRRL 3510 and Fusarium poae 3287. Jpn J Exp Med. 1972 Oct;42(5):461–472. [PubMed] [Google Scholar]
- Ueno Y., Sato N., Ishii K., Sakai K., Tsunoda H. Biological and chemical detection of trichothecene mycotoxins of Fusarium species. Appl Microbiol. 1973 Apr;25(4):699–704. doi: 10.1128/am.25.4.699-704.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ueno Y., Sawano M., Ishii K. Production of trichothecene mycotoxins by Fusarium species in shake culture. Appl Microbiol. 1975 Jul;30(1):4–9. doi: 10.1128/am.30.1.4-9.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]