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. 1995 May;2(3):381–384. doi: 10.1128/cdli.2.3.381-384.1995

Impaired expression of interleukin 2 receptor and CD45RO antigen on lymphocytes from children with acute lymphoblastic leukemia in response to cytomegalovirus and varicella-zoster virus.

K Mizutani 1, M Ito 1, T Nakano 1, H Kamiya 1, M Sakurai 1
PMCID: PMC170164  PMID: 7664187

Abstract

The expression of CD25 and CD45RO in lymphocytes from patients with acute lymphoblastic leukemia in response to cytomegalovirus and varicella-zoster virus antigens was analyzed by flow cytometry. It is suggested that the defects in the immune response to cytomegalovirus and varicella-zoster virus in patients with acute lymphoblastic leukemia on chemotherapy are in the expression of CD25 and in the switching of CD45RA cells to CD45RO cells.

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Selected References

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