Skip to main content
NCBI home page
British Medical Journal logoLink to British Medical Journal
. 1970 Jul 18;3(5715):143–146. doi: 10.1136/bmj.3.5715.143

Hyperglobulinaemic Renal Tubular Acidosis: A Report of Nine Cases

Alastair M S Mason, Peter L Golding
PMCID: PMC1702262  PMID: 4193999

Abstract

Of nine women with hyperglobulinaemic renal tubular acidosis four presented with acidosis and five had the “incomplete” form of the disorder. Seven patients had nephrogenic diabetes insipidus, but none had the Fanconi syndrome. Investigation showed abnormal immunoglobulins and autoantibodies in all nine patients. Diseases coexisting with renal tubular acidosis were Sjögren's syndrome, hyperglobulinaemic purpura, autoimmune liver and thyroid disease, diffuse pulmonary fibrosis, and a peripheral neuropathy. It is suggested that this type of renal tubular acidosis might be due to an autoimmune process.

Full text

PDF
143

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bennett W. M., Hempel K. H., Berland J. E., Porter G. A. Renal tubular acidosis. Arch Intern Med. 1968 Jan;121(1):81–86. [PubMed] [Google Scholar]
  2. COHEN A., WAY B. J. The association of renal tubular acidosis with hyperglobulinaemic purpura. Australas Ann Med. 1962 Aug;11:189–194. doi: 10.1111/imj.1962.11.3.189. [DOI] [PubMed] [Google Scholar]
  3. FOSS G. L., PERRY C. B., WOOD F. J. Renal tubular acidosis. Q J Med. 1956 Apr;25(98):185–199. [PubMed] [Google Scholar]
  4. HUTH E. J., MAYOCK R. L., KERR R. M. Hyperthyroidism associated with renal tubular acidosis; discussion of possible relationship. Am J Med. 1959 May;26(5):818–826. doi: 10.1016/0002-9343(59)90240-2. [DOI] [PubMed] [Google Scholar]
  5. Kaltreider H. B., Talal N. The neuropathy of Sjögren's syndrome. Trigeminal nerve involvement. Ann Intern Med. 1969 Apr;70(4):751–762. doi: 10.7326/0003-4819-70-4-751. [DOI] [PubMed] [Google Scholar]
  6. Leeson P. M., Fourman P. A disorder of copper metabolism treated with penicillamine in a patient with primary biliary cirrhosis and renal tubular acidosis. Am J Med. 1967 Oct;43(4):620–635. doi: 10.1016/0002-9343(67)90185-4. [DOI] [PubMed] [Google Scholar]
  7. McCurdy D. K., Cornwell G. G., 3rd, DePratti V. J. Hyperglobulinemic renal tubular acidosis. Report of two cases. Ann Intern Med. 1967 Jul;67(1):110–117. doi: 10.7326/0003-4819-67-1-110. [DOI] [PubMed] [Google Scholar]
  8. Morris R. C., Jr, Fudenberg H. H. Impaired renal acidification in patients with hypergammaglobulinemia. Medicine (Baltimore) 1967 Jan;46(1):57–69. doi: 10.1097/00005792-196701000-00003. [DOI] [PubMed] [Google Scholar]
  9. Morris R. C., Jr Renal tubular acidosis. Mechanisms, classification and implications. N Engl J Med. 1969 Dec 18;281(25):1405–1413. doi: 10.1056/NEJM196912182812508. [DOI] [PubMed] [Google Scholar]
  10. PINES K. L., MUDGE G. H. Renal tubular acidosis with osteomalacia; report of 3 cases. Am J Med. 1951 Sep;11(3):302–311. doi: 10.1016/0002-9343(51)90167-2. [DOI] [PubMed] [Google Scholar]
  11. READ A. E., SHERLOCK S., HARRISON C. V. ACTIVE 'JUVENILE' CIRRHOSIS CONSIDERED AS PART OF A SYSTEMIC DISEASE AND THE EFFECT OF CORTICOSTEROID THERAPY. Gut. 1963 Dec;4:378–393. doi: 10.1136/gut.4.4.378. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. SHEARN M. A., TU W. H. NEPHROGENIC DIABETIC INSIPIDUS AND OTHER DEFECTS OF RENAL TUBULAR FUNCTION IN SJOERGREN'S SYNDROME. Am J Med. 1965 Aug;39:312–318. doi: 10.1016/0002-9343(65)90057-4. [DOI] [PubMed] [Google Scholar]
  13. Seedat Y. K., Raine E. R. Active chronic hepatitis associated with renal tubular acidosis and successful pregnancy. S Afr Med J. 1965 Jul 17;39(26):595–597. [PubMed] [Google Scholar]
  14. Shearn M. A., Tu W. H. Latent renal tubular acidosis in Sjøgren's syndrome. Ann Rheum Dis. 1968 Jan;27(1):27–32. doi: 10.1136/ard.27.1.27. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Smith P. M., Middleton J. E., Williams R. Renal tubular acidosis and cirrhosis. Postgrad Med J. 1967 Jun;43(500):439–442. [PMC free article] [PubMed] [Google Scholar]
  16. Talal N., Zisman E., Schur P. H. Renal tubular acidosis, glomerulonephritis and immunologic factors in Sjögren's syndrome. Arthritis Rheum. 1968 Dec;11(6):774–786. doi: 10.1002/art.1780110607. [DOI] [PubMed] [Google Scholar]
  17. WRONG O., DAVIES H. E. The excretion of acid in renal disease. Q J Med. 1959 Apr;28(110):259–313. [PubMed] [Google Scholar]
  18. WRONG O. URINARY HYDROGEN ION EXCRETION. J Clin Pathol. 1965 Jul;18:520–526. [PubMed] [Google Scholar]
  19. Wilson I. D., Williams R. C., Tobian L., Jr Renal tubular acidosis. Three cases with immunoglobulin abnormalities in the patients and their kindreds. Am J Med. 1967 Sep;43(3):356–370. doi: 10.1016/0002-9343(67)90192-1. [DOI] [PubMed] [Google Scholar]
  20. Zisman E., Buccino R. A., Gorden P., Bartter F. Hyperthyroidism and renal tubular acidosis. Arch Intern Med. 1968 Feb;121(2):118–122. [PubMed] [Google Scholar]

Articles from British Medical Journal are provided here courtesy of BMJ Publishing Group

RESOURCES