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. 1970 Jan;38(1):206–213.

The assay of gastrin using the perfused rat stomach

G M Smith, A J Lawrence, D G Colin-Jones, H O Schild
PMCID: PMC1702629  PMID: 5413287

Abstract

1. A method is described for the bio-assay of gastric secretagogues using the perfused rat stomach in which the acid output can be readily and accurately quantified.

2. This technique increases the sensitivity of the perfused rat stomach so that 10-20 ng of synthetic human gastrin I can be detected.

3. It is possible to assay secretagogues, relative to a standard with fiducial limits of less than ±30%.

4. The use of this system is illustrated by assays comparing synthetic human gastrin I with pentagastrin, pure hog gastrin and gastrin added to plasma.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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