Abstract
1. The influence of sodium and potassium on the accumulation of 5-hydroxytryptamine (5-HT) by rat blood platelets was investigated.
2. An absolute dependence of 5-HT uptake on the sodium concentration in the medium was found.
3. Removal of potassium reduced the uptake by about 60%. High concentrations of potassium inhibited sodium-dependent accumulation.
4. The observations have been discussed in terms of a carrier-mediated transport process for 5-HT operating in the platelet membrane.
Full text
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
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