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British Journal of Pharmacology and Chemotherapy logoLink to British Journal of Pharmacology and Chemotherapy
. 1964 Jun;22(3):486–498. doi: 10.1111/j.1476-5381.1964.tb01703.x

Histamine protection produced by plant tumour extracts. The active principle of tomato plants infected with crown-gall

D H Calam, R K Callow
PMCID: PMC1703940  PMID: 14211679

Abstract

Guinea-pigs were protected against the lethal effects of a histamine aerosol by intraperitoneal injection of stable extracts of normal tomato plants and of tomato plants infected with crown-gall tumours. The protection was short-lasting. No difference was observed between the activities of extracts of normal and of infected plants. The active principle of the extracts was isolated, and identified as the steroid alkaloid glycoside, tomatine.

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Selected References

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