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. 1979 Aug 18;121(4):428-30, 433-4.

Familial hypogonadotropic hypogonadism with alopecia.

I S Slti, Z Salem
PMCID: PMC1704396  PMID: 466617

Abstract

In one family several male and female members had hypogonadism and frontoparietal alopecia, whereas other members with normal sexual development had normal scalp hair. Clinical and laboratory evaluation of three affected young men (two brothers and their cousin) revealed that the hypogonadism was the result of decreased serum concentrations of follicle stimulating and luteinizing hormones. There was no evidence of a deficiency of any other pituitary hormone. Long-term treatment of the three patients with human chorionic gonadotropin resulted in an increase in the serum testosterone concentration, the appearance of male secondary sex characteristics and an increase in the size of the external genitalia.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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