Abstract
Infusions and extracts of different grapes inactivated poliovirus; agents responsible for this property resided in the skin of the grape. Commercial grape juice at both natural and neutral pH inactivate various enteric viruses and herpes simplex virus; a 1,000-fold reduction in poliovirus infectivity occurred after incubation with grape juice, pH 7.0, for 24 h at 4 degrees C. A variety of wines were antiviral but to a lesser extent than grape juice; red wines were more antiviral than white. Antiviral activity was demonstrable in fractions of grape juice varying in molecular weight from less than 1,000 to greater than 30,000 as determined by membrane filtration. Some restoration of poliovirus infectivity from virus-grape juice complexes was achieved with 1% gelatin, 0.1% Tween 80, 0.5% polyvinyl pyrrolidone, and 0.5% polyethylene glycol.
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Selected References
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- CARSON R. S., FRISCH A. W. The inactivation of influenza viruses by tannic acid and related compounds. J Bacteriol. 1953 Nov;66(5):572–575. doi: 10.1128/jb.66.5.572-575.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Herrmann E. C., Jr, Kucera L. S. Antiviral substances in plants of the mint family (labiatae). 3. Peppermint (Mentha piperita) and other mint plants. Proc Soc Exp Biol Med. 1967 Mar;124(3):874–878. doi: 10.3181/00379727-124-31874. [DOI] [PubMed] [Google Scholar]
- Herrmann E. C., Jr, Kucera L. S. Antiviral substances in plants of the mint family (labiatae). II. Nontannin polyphenol of Melissa officinalis. Proc Soc Exp Biol Med. 1967 Mar;124(3):869–874. doi: 10.3181/00379727-124-31873. [DOI] [PubMed] [Google Scholar]
- Konowalchuk J., Speirs J. I. Enterovirus recovery with vegetable floc. Appl Microbiol. 1973 Oct;26(4):505–507. doi: 10.1128/am.26.4.505-507.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kucera L. S., Herrmann E. C., Jr Antiviral substances in plants of the mint family (labiatae). I. Tannin of Melissa officinalis. Proc Soc Exp Biol Med. 1967 Mar;124(3):865–869. doi: 10.3181/00379727-124-31872. [DOI] [PubMed] [Google Scholar]