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Clinical and Diagnostic Laboratory Immunology logoLink to Clinical and Diagnostic Laboratory Immunology
. 1997 Jan;4(1):104–106. doi: 10.1128/cdli.4.1.104-106.1997

Antibody production against hepatitis C virus core and nonstructural 3 proteins is highly sensitive to deficits in T-cell function.

Y Ando 1, A Sönnerborg 1, L Barkholt 1, A Birkett 1, B G Ericzon 1, M Sällberg 1
PMCID: PMC170485  PMID: 9008291

Abstract

The influence of suppression of CD4+ and CD8+ T cells on the humoral responses to hepatitis C virus (HCV) core and nonstructural 3 proteins was studied. An increasing viral burden cannot substitute for the lack of functional T cells in maintaining humoral HCV-specific responses.

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Selected References

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