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. 1980 Nov 8;123(9):850–856.

Dietary fibre and colon cancer: epidemiologic and experimental evidence.

B S Reddy
PMCID: PMC1704898  PMID: 6254626

Abstract

Epidemiologic studies have identified two dietary factors, a relatively high intake of fat and a relatively low intake of fibre, that are associated with colon cancer in humans. However, a recent study has shown a low risk of large bowel cancer in a rural Finnish population with a high dietary intake of fat, but also a high intake of fibre. Observations in humans and studies in animals have indicated that dietary fibre may protect against colon carcinogenesis by binding bile acids in the intestinal tract, by a direct effect on the colonic mucosa and by an indirect effect on the metabolism of carcinogens. The strength of protection varies with the type of fibre.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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