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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1981 Jan 1;124(1):42–47.

Bleeding varices: 2. Elective management.

S S Hanna, W D Warren, J T Galambos, W J Millikan Jr
PMCID: PMC1705090  PMID: 7006780

Abstract

Patients who have previously bled from esophageal varices should have their hepatic function, neurologic status and nutritional status evaluated and should be examined for ascites before elective variceal decompression is done to prevent recurrent variceal hemorrhage. The two most important procedures used for this evaluation are liver biopsy and visceral angiography. If the liver biopsy reveals little or no necroinflammatory activity, shunt surgery is indicated. For patients with moderate or severe necroinflammatory activity, surgery is delayed until the inflammation subsides. The central aim of visceral angiography is to determine whether the patient has hepatopetal or hepatofugal portal venous flow. Patients with hepatopetal flow are treated with a selective distal splenorenal shunt. Those with hepatofugal flow are managed with a total shunt, such as an interposition H-graft portacaval or mesocaval shunt.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Belli L., Marni A. Alternative use of the interposition Dacron grafts in the treatment of portal hypertension. Clinical experience with 28 cases. J Cardiovasc Surg (Torino) 1978 Sep-Oct;19(5):527–534. [PubMed] [Google Scholar]
  2. Bergan A., Flatmark A. Operative results in portal hypertension with bleeding oesophageal varices. Scand J Gastroenterol. 1977;12(6):677–682. doi: 10.3109/00365527709181703. [DOI] [PubMed] [Google Scholar]
  3. Busuttil R. W., Brin B., Tompkins R. K. Matched control study of distal splenorenal and portacaval shunts in the treatment of bleeding esophageal varices. Am J Surg. 1979 Jul;138(1):62–67. doi: 10.1016/0002-9610(79)90243-5. [DOI] [PubMed] [Google Scholar]
  4. CONN H. O., LINDENMUTH W. W. PROPHYLACTIC PORTACAVAL ANASTOMOSIS IN CIRRHOTIC PATIENTS WITH ESOPHAGEAL VARICES: A PROGRESS REPORT OF A CONTINUING STUDY. N Engl J Med. 1965 Jun 17;272:1255–1263. doi: 10.1056/NEJM196506172722402. [DOI] [PubMed] [Google Scholar]
  5. Child C. G., Turcotte J. G. Surgery and portal hypertension. Major Probl Clin Surg. 1964;1:1–85. [PubMed] [Google Scholar]
  6. Conn H. O., Lindenmuth W. W. Prophylactic portacaval anastomosis in cirrhotic patients with esophageal varices and ascites. Experimental design and preliminary results. Am J Surg. 1969 May;117(5):656–661. doi: 10.1016/0002-9610(69)90401-2. [DOI] [PubMed] [Google Scholar]
  7. Cooperman A. M., Hermann R. E. Ligation procedures in the management of portal hypertension. Surgery. 1977 Apr;81(4):382–385. [PubMed] [Google Scholar]
  8. Dowling J. B. Ten years' experience with mesocaval grafts. Surg Gynecol Obstet. 1979 Oct;149(4):518–522. [PubMed] [Google Scholar]
  9. Ferrara J., Ellison E. C., Martin E. W., Jr, Cooperman M. Correction of hypersplenism following distal splenorenal shunt. Surgery. 1979 Oct;86(4):570–573. [PubMed] [Google Scholar]
  10. George P., Brown C., Ridgway G., Crofts B., Sherlock S. Emergency oesophageal transection in uncontrolled variceal haemorrhage. Br J Surg. 1973 Aug;60(8):635–640. doi: 10.1002/bjs.1800600815. [DOI] [PubMed] [Google Scholar]
  11. Habashi A. H. Trans-splenic decompression of oesophageal varices by selective distal splenorenal shunt. J Egypt Med Assoc. 1977;60(1-2):23–38. [PubMed] [Google Scholar]
  12. Inokuchi K., Kobayashi M., Saku M., Nagasue N., Iwaki A. Transthoracic cardiectomy with infraesophago-supragastric devascularization for bleeding esophageal varices. Jpn J Surg. 1977 Sep;7(3):123–140. doi: 10.1007/BF02469342. [DOI] [PubMed] [Google Scholar]
  13. Jackson F. C., Perrin E. B., Felix W. R., Smith A. G. A clinical investigation of the portacaval shunt. V. Survival analysis of the therapeutic operation. Ann Surg. 1971 Oct;174(4):672–701. doi: 10.1097/00000658-197110000-00012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. Jackson F. C., Perrin E. B., Smith A. G., Dagradi A. E., Nadal H. M. A clinical investigation of the portacaval shunt. II. Survival analysis of the prophylactic operation. Am J Surg. 1968 Jan;115(1):22–42. doi: 10.1016/0002-9610(68)90127-x. [DOI] [PubMed] [Google Scholar]
  15. Johnston G. W. Simplified oesophageal transection for bleeding varices. Br Med J. 1978 May 27;1(6124):1388–1391. doi: 10.1136/bmj.1.6124.1388. [DOI] [PMC free article] [PubMed] [Google Scholar]
  16. Johnston G. W. Ten years of portal systemic shunts. Ulster Med J. 1977;46(2):113–118. [PMC free article] [PubMed] [Google Scholar]
  17. Langer B., Patel S. C., Stone R. M., Colapinto R. F., Phillips M. J., Fisher M. M. Selection of operation in patients with bleeding esophageal varices. Can Med Assoc J. 1978 Feb 18;118(4):369–372. [PMC free article] [PubMed] [Google Scholar]
  18. Macpherson A. I., Finlayson N. D. Oesophageal transection for portal hypertension in the poor risk patient. J R Coll Surg Edinb. 1976 Mar;21(2):90–94. [PubMed] [Google Scholar]
  19. Maillard J. N., Flamant Y. M., Hay J. M., Chandler J. G. Selectivity of the distal splenorenal shunt. Surgery. 1979 Nov;86(5):663–671. [PubMed] [Google Scholar]
  20. Martin E. W., Jr, Molnar J., Cooperman M., Pace W. G., Thomford N. R., Carey L. C. Observations on fifty distal splenorenal shunts. Surgery. 1978 Sep;84(3):379–383. [PubMed] [Google Scholar]
  21. Mikkelsen W. P. Therapeutic portacaval shunt. Preliminary data on controlled trial and morbid effects of acute hyaline necrosis. Arch Surg. 1974 Mar;108(3):302–305. doi: 10.1001/archsurg.1974.01350270036007. [DOI] [PubMed] [Google Scholar]
  22. Mikkelsen W. P., Turrill F. L., Kern W. H. Acute hyaline necrosis of the liver. A surgical trap. Am J Surg. 1968 Aug;116(2):266–272. doi: 10.1016/0002-9610(68)90503-5. [DOI] [PubMed] [Google Scholar]
  23. Mosimann R., Loup P. Efficacy and risks of the distal splenorenal shunt in the treatment of bleeding esophageal varices. Am J Surg. 1977 Feb;133(2):163–168. doi: 10.1016/0002-9610(77)90072-1. [DOI] [PubMed] [Google Scholar]
  24. Paris J. C., Ribet M., Quandalle P., Roger J., Houcke P. Etude critique de l'anastomose mésentérico-cave en H chez le cirrhotique. Acta Gastroenterol Belg. 1978 Sep-Oct;41(9-10):522–526. [PubMed] [Google Scholar]
  25. Pera C., Visa J., Rodes J., Teres J. Preliminary trial of a retroperitoneal approach for modified selective distal splenorenal shunt. World J Surg. 1978 Sep;2(5):653–658. doi: 10.1007/BF01556070. [DOI] [PubMed] [Google Scholar]
  26. Pierce G. E., Thomas J. H., Estes N. C. A transthoracic devascularization procedure for control of bleeding esophageal varices: preliminary report. Am J Surg. 1977 Dec;134(6):794–798. doi: 10.1016/0002-9610(77)90327-0. [DOI] [PubMed] [Google Scholar]
  27. Reichle F. A., Fahmy W. F., Golsorkhi M. Prospective comparative clinical trial with distal splenorenal and mesocaval shunts. Am J Surg. 1979 Jan;137(1):13–21. doi: 10.1016/0002-9610(79)90004-7. [DOI] [PubMed] [Google Scholar]
  28. Resnick R. H., Chalmers T. C., Ishihara A. M., Garceau A. J., Callow A. D., Schimmel E. M., O'Hara E. T. A controlled study of the prophylactic portacaval shunt. A final report. Ann Intern Med. 1969 Apr;70(4):675–688. doi: 10.7326/0003-4819-70-4-675. [DOI] [PubMed] [Google Scholar]
  29. Rikkers L. F., Rudman D., Galambos J. T., Fulenwider J. T., Millikan W. J., Kutner M., Smith R. B., 3rd, Salam A. A., Sones P. J., Jr, Warren W. D. A randomized, controlled trial of the distal splenorenal shunt. Ann Surg. 1978 Sep;188(3):271–282. doi: 10.1097/00000658-197809000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Rikkers L., Jenko P., Rudman D., Freides D. Subclinical hepatic encephalopathy: detection, prevalence, and relationship to nitrogen metabolism. Gastroenterology. 1978 Sep;75(3):462–469. [PubMed] [Google Scholar]
  31. Rothwell-Jackson R. L., Hunt A. H. The results obtained with emergency surgery in the treatment of persistent haemorrhage from gastro-oesophageal varices in the cirrhotic patient. Br J Surg. 1971 Mar;58(3):205–215. doi: 10.1002/bjs.1800580314. [DOI] [PubMed] [Google Scholar]
  32. Rudman D., DiFulco T. J., Galambos J. T., Smith R. B., 3rd, Salam A. A., Warren W. D. Maximal rates of excretion and synthesis of urea in normal and cirrhotic subjects. J Clin Invest. 1973 Sep;52(9):2241–2249. doi: 10.1172/JCI107410. [DOI] [PMC free article] [PubMed] [Google Scholar]
  33. Rueff B., Prandi D., Degos F., Sicot J., Degos J. D., Sicot C., Maillard J. N., Fauvert R., Benhamou J. P. A controlled study of therapeutic portacaval shunt in alcoholic cirrhosis. Lancet. 1976 Mar 27;1(7961):655–659. doi: 10.1016/s0140-6736(76)92775-6. [DOI] [PubMed] [Google Scholar]
  34. Stoney R. J., Olcott C., 4th Renosplenic shunt for control of esophageal variceal hemorrhage. Am J Surg. 1978 Mar;135(3):432–435. doi: 10.1016/0002-9610(78)90080-6. [DOI] [PubMed] [Google Scholar]
  35. Sugiura M., Futagawa S. Further evaluation of the Sugiura procedure in the treatment of esophageal varices. Arch Surg. 1977 Nov;112(11):1317–1321. doi: 10.1001/archsurg.1977.01370110051005. [DOI] [PubMed] [Google Scholar]
  36. Takasaki T., Kobayashi S., Muto H., Suzuki S., Harada M., Nakayama K. Transabdominal esophageal transection by using a suture device in cases of esophageal varices. Int Surg. 1977 Aug;62(8):426–428. [PubMed] [Google Scholar]
  37. Thompson B. W., Casali R. E., Read R. C., Campbell G. S. Results of interposition "H" grafts for portal hypertension. Ann Surg. 1978 May;187(5):515–522. doi: 10.1097/00000658-197805000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Vang J., Simert G., Hansson J. A., Thylen U., Bengmark T. S. Results of a modified distal spleno-renal shunt for portal hypertension. Ann Surg. 1977 Feb;185(2):224–228. doi: 10.1097/00000658-197702000-00016. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Warren W. D., Salam A. A., Hutson D., Zeppa R. Selective distal splenorenal shunt. Technique and results of operation. Arch Surg. 1974 Mar;108(3):306–314. doi: 10.1001/archsurg.1974.01350270040008. [DOI] [PubMed] [Google Scholar]
  40. Warren W. D., Zeppa R., Fomon J. J. Selective trans-splenic decompression of gastroesophageal varices by distal splenorenal shunt. Ann Surg. 1967 Sep;166(3):437–455. doi: 10.1097/00000658-196709000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Windle R., Peacock J. H. Prognosis after portocaval anastomosis: a 15-year follow-up. Br J Surg. 1975 Sep;62(9):701–706. doi: 10.1002/bjs.1800620908. [DOI] [PubMed] [Google Scholar]
  42. Yamamoto S., Hidemura R., Sawada M., Takeshige K., Iwatsuki S. The late results of terminal esophagoproximal gastrectomy (TEPG) with intensive devascularization and splenectomy for bleeding esophageal varices in cirrhosis. Surgery. 1976 Jul;80(1):106–114. [PubMed] [Google Scholar]
  43. Zeppa R., Hensley G. T., Levi J. U., Bergstresser P. R., Hutson D. G., Sr, Livingstone A. S., Schiff E. R., Fink P. The comparative survivals of alcoholics versus nonalcoholics after distal splenorenal shunt. Ann Surg. 1978 May;187(5):510–514. doi: 10.1097/00000658-197805000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  44. Zeppa R., Hutson D. G., Sr, Bergstresser P. R., Levi J. U., Schiff E. R., Fink P. Survival after distal splenorenal shunt. Surg Gynecol Obstet. 1977 Jul;145(1):12–16. [PubMed] [Google Scholar]

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