Skip to main content
Applied and Environmental Microbiology logoLink to Applied and Environmental Microbiology
. 1977 Apr;33(4):1016–1018. doi: 10.1128/aem.33.4.1016-1018.1977

Unaltered Metabolism of Taurolithocholic Acid with Changes in Composition of Rat Intestinal Microflora

M I Kelsey 1, S Sexton 1, G E Fulk 1, K-T Chung 1
PMCID: PMC170815  PMID: 559471

Abstract

Changes in composition of both total aerobes and anaerobes of rat intestinal microflora do not appear to affect the metabolism of taurolithocholic acid.

Full text

PDF
1016

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ames B. N., Durston W. E., Yamasaki E., Lee F. D. Carcinogens are mutagens: a simple test system combining liver homogenates for activation and bacteria for detection. Proc Natl Acad Sci U S A. 1973 Aug;70(8):2281–2285. doi: 10.1073/pnas.70.8.2281. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Campbell R. L., Singh D. V., Nigro N. D. Importance of the fecal stream on the induction of colon tumors by azoxymethane in rats. Cancer Res. 1975 May;35(5):1369–1371. [PubMed] [Google Scholar]
  3. Elliott W. H., Hyde P. M. Metabolic pathways of bile acid synthesis. Am J Med. 1971 Nov;51(5):568–579. doi: 10.1016/0002-9343(71)90281-6. [DOI] [PubMed] [Google Scholar]
  4. Hiasa Y., Konishi Y., Kamamoto Y., Watanabe T., Ito N. Effect of lithocholic acid on DL-ethionine carcinogenesis in rat liver. Gan. 1971 Aug;62(4):239–245. [PubMed] [Google Scholar]
  5. Kelsey M. I., Sexton S. A. The biosynthesis of ethyl esters of lithocholic acid and isolithocholic acid by rat intestinal microflora. J Steroid Biochem. 1976 Sep;7(9):641–647. doi: 10.1016/0022-4731(76)90059-5. [DOI] [PubMed] [Google Scholar]
  6. Kelsey M. I., Thompson R. J. The biosynthesis of ethyl lithocholate by fecal microorganisms. J Steroid Biochem. 1976 Feb;7(2):117–124. doi: 10.1016/0022-4731(76)90146-1. [DOI] [PubMed] [Google Scholar]
  7. Narisawa T., Magadia N. E., Weisburger J. H., Wynder E. L. Promoting effect of bile acids on colon carcinogenesis after intrarectal instillation of N-methyl-N'-nitro-N-nitrosoguanidine in rats. J Natl Cancer Inst. 1974 Oct;53(4):1093–1097. doi: 10.1093/jnci/53.4.1093. [DOI] [PubMed] [Google Scholar]

Articles from Applied and Environmental Microbiology are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES