Abstract
Twenty strains of lactobacilli isolated from the stomach of conventional mice were tested for their ability to ferment or hydrolyze substrates that may be present in the stomach habitat. The lactobacilli could be placed in four groups (A to D) depending on their ability to ferment N-acetylglucosamine, dextrin, cellobiose, gum arabic, and xylan. The majority of the isolates belonged to groups A and D. Group A strains did not resemble previously described Lactobacillus species, but group D strains were identified as L. leichmannii. A representative group A isolate colonized the surface of the nonsecretory epithelium of the stomach of gnotobiotic mice; a group D isolate did not.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bauchop T. Stomach microbiology of primates. Annu Rev Microbiol. 1971;25:429–436. doi: 10.1146/annurev.mi.25.100171.002241. [DOI] [PubMed] [Google Scholar]
- Brooker B. E., Fuller R. Adhesion of Lactobacilli to the chicken crop epithelium. J Ultrastruct Res. 1975 Jul;52(1):21–31. doi: 10.1016/s0022-5320(75)80019-0. [DOI] [PubMed] [Google Scholar]
- DUBOS R., SCHAEDLER R. W., COSTELLO R., HOET P. INDIGENOUS, NORMAL, AND AUTOCHTHONOUS FLORA OF THE GASTROINTESTINAL TRACT. J Exp Med. 1965 Jul 1;122:67–76. doi: 10.1084/jem.122.1.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Fuller R., Brooker B. E. Lactobacilli which attach to the crop epithelium of the fowl. Am J Clin Nutr. 1974 Nov;27(11):1305–1312. doi: 10.1093/ajcn/27.11.1305. [DOI] [PubMed] [Google Scholar]
- Fuller R. Nature of the determinant responsible for the adhesion of lactobacilli to chicken crop epithelial cells. J Gen Microbiol. 1975 Apr;87(2):245–250. doi: 10.1099/00221287-87-2-245. [DOI] [PubMed] [Google Scholar]
- Gibbons R. J., Fitzgerald R. J. Dextran-induced agglutination of Streptococcus mutans, and its potential role in the formation of microbial dental plaques. J Bacteriol. 1969 May;98(2):341–346. doi: 10.1128/jb.98.2.341-346.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
- HUNGATE R. E. The anaerobic mesophilic cellulolytic bacteria. Bacteriol Rev. 1950 Mar;14(1):1–49. doi: 10.1128/br.14.1.1-49.1950. [DOI] [PMC free article] [PubMed] [Google Scholar]
- LESHER S., WALBURG H. E., Jr, SACHER G. A., Jr GENERATION CYCLE IN THE DUODENAL CRYPT CELLS OF GERM-FREE AND CONVENTIONAL MICE. Nature. 1964 May 30;202:884–886. doi: 10.1038/202884a0. [DOI] [PubMed] [Google Scholar]
- McCabe R. M., Keyes P. H., Howell A., Jr An in vitro method for assessing the plaque forming ability of oral bacteria. Arch Oral Biol. 1967 Dec;12(12):1653–1656. doi: 10.1016/0003-9969(67)90200-2. [DOI] [PubMed] [Google Scholar]
- SCHAEDLER R. W., DUBOS R. J. The fecal flora of various strains of mice. Its bearing on their susceptibility to endotoxin. J Exp Med. 1962 Jun 1;115:1149–1160. doi: 10.1084/jem.115.6.1149. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Savage D. C. Associations and physiological interactions of indigenous microorganisms and gastrointestinal epithelia. Am J Clin Nutr. 1972 Dec;25(12):1372–1379. doi: 10.1093/ajcn/25.12.1372. [DOI] [PubMed] [Google Scholar]
- Savage D. C., Blumershine R. V. Surface-surface associations in microbial communities populating epithelial habitats in the murine gastrointestinal ecosystem: scanning electron microscopy. Infect Immun. 1974 Jul;10(1):240–250. doi: 10.1128/iai.10.1.240-250.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Savage D. C., Dubos R., Schaedler R. W. The gastrointestinal epithelium and its autochthonous bacterial flora. J Exp Med. 1968 Jan 1;127(1):67–76. doi: 10.1084/jem.127.1.67. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Savage D. C., McAllister J. S., Davis C. P. Anaerobic bacteria on the mucosal epithelium of the murine large bowel. Infect Immun. 1971 Oct;4(4):492–502. doi: 10.1128/iai.4.4.492-502.1971. [DOI] [PMC free article] [PubMed] [Google Scholar]
- TREXLER P. C., REYNOLDS L. I. Flexible film apparatus for the rearing and use of germfree animals. Appl Microbiol. 1957 Nov;5(6):406–412. doi: 10.1128/am.5.6.406-412.1957. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tannock G. W., Savage D. C. Influences of dietary and environmental stress on microbial populations in the murine gastrointestinal tract. Infect Immun. 1974 Mar;9(3):591–598. doi: 10.1128/iai.9.3.591-598.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tannock G. W., Smith J. M. The effect of food and water deprivation (stress) on Salmonella-carrier mice. J Med Microbiol. 1972 Aug;5(3):283–289. doi: 10.1099/00222615-5-3-283. [DOI] [PubMed] [Google Scholar]
- Tannock G. W., Smith J. M. The microflora of the pig stomach and its possible relationship to ulceration of the pars oesophagea. J Comp Pathol. 1970 Jul;80(3):359–367. doi: 10.1016/0021-9975(70)90066-6. [DOI] [PubMed] [Google Scholar]