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. 1981 Jan;37(1):483–487. doi: 10.1128/jvi.37.1.483-487.1981

Resistance of cultures of normal T cells to infection with murine type C viruses.

I Horak, L Enjuanes, J C Lee, J N Ihle
PMCID: PMC171025  PMID: 6260996

Abstract

Long-term continuous cultures of normal T cells were established from C57BL/6 and BALB/c mice by using conditioned medium from concanavalin A-stimulated lymphocytes. The ability of various murine type C viruses to infect these normal T cell cultures was examined and compared with their ability to infect transformed T cells. All of the viruses examined, including a thymotropic radiation leukemia virus, were unable to infect and replicate in normal T cells but readily did so in transformed T cells.

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Selected References

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