Abstract
Infection of KB cells by adenovirus normally results in a drastic reduction of host DNA synthesis at 33 to 37 degrees C. This inhibition was largely reversed by raising the temperature to 41 degrees C. Inhibition was reinstated if the temperature is lowered.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Botchan M., Topp W., Sambrook J. The arrangement of simian virus 40 sequences in the DNA of transformed cells. Cell. 1976 Oct;9(2):269–287. doi: 10.1016/0092-8674(76)90118-5. [DOI] [PubMed] [Google Scholar]
- Chen S., Zubay G., Ginsberg H. S. The replication pattern of adenovirus DNA in vivo reproduced in vitro. Eur J Biochem. 1980 Mar;104(2):587–594. doi: 10.1111/j.1432-1033.1980.tb04462.x. [DOI] [PubMed] [Google Scholar]
- DePamphilis M. L., Anderson S., Bar-Shavit R., Collins E., Edenberg H., Herman T., Karas B., Kaufmann G., Krokan H., Shelton E. Replication and structure of simian virus 40 chromosomes. Cold Spring Harb Symp Quant Biol. 1979;43(Pt 2):679–692. doi: 10.1101/sqb.1979.043.01.076. [DOI] [PubMed] [Google Scholar]
- Ginsberg H. S., Ensinger M. J., Kauffman R. S., Mayer A. J., Lundholm U. Cell transformation: a study of regulation with types 5 and 12 adenovirus temperature-sensitive mutants. Cold Spring Harb Symp Quant Biol. 1975;39(Pt 1):419–426. doi: 10.1101/sqb.1974.039.01.054. [DOI] [PubMed] [Google Scholar]
- Longiaru M., Ikeda J. E., Jarkovsky Z., Horwitz S. B., Horwitz M. S. The effect of aphidicolin on adenovirus DNA synthesis. Nucleic Acids Res. 1979 Jul 25;6(10):3369–3386. doi: 10.1093/nar/6.10.3369. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mak S., Green M. Biochemical studies on adenovirus multiplication. 13. Synthesis of virus-specific ribonucleic acid during infection with human adenovirus type 12. J Virol. 1968 Oct;2(10):1055–1063. doi: 10.1128/jvi.2.10.1055-1063.1968. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ohashi M., Taguchi T., Ikegami S. Aphidicolin: a specific inhibitor of DNA polymerases in the cytosol of rat liver. Biochem Biophys Res Commun. 1978 Jun 29;82(4):1084–1090. doi: 10.1016/0006-291x(78)90298-x. [DOI] [PubMed] [Google Scholar]