Abstract
Epstein Barr virus (EBV) and herpesvirus papio (HVPapio) DNAs share a common format and 40% homology. Labeled cloned fragments of EBV DNA were hybridized to blots of XbaI, EcoRI, HindIII, and SalI fragments of HVPapio DNA. EBV fragments which mapped from 2 x 10(6) to 54 x 10(6) and from 59 x 10(6) to 106 x 10(6) daltons hybridized to fragments at identical map positions in HVPapio DNA. Regions of nonhomology were demonstrated at 0 x 10(6) to 2 x 10(6), 54 x 10(6) to 59 10(6), and 106 x 10(6) to 115 x 10(6) daltons.
Full text
PDF





Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Botstein D., Herskowitz I. Properties of hybrids between Salmonella phage P22 and coliphage lambda. Nature. 1974 Oct 18;251(5476):584–589. doi: 10.1038/251584a0. [DOI] [PubMed] [Google Scholar]
- Falk L., Deinhardt F., Nonoyama M., Wolfe L. G., Bergholz C. Properties of a baboon lymphotropic herpesvirus related to Epstein-Barr virus. Int J Cancer. 1976 Dec 15;18(6):798–807. doi: 10.1002/ijc.2910180611. [DOI] [PubMed] [Google Scholar]
- Gerber P., Birch S. M. Complement-fixing antibodies in sera of human and nonhuman primates to viral antigens derived from Burkitt's lymphoma cells. Proc Natl Acad Sci U S A. 1967 Aug;58(2):478–484. doi: 10.1073/pnas.58.2.478. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gerber P., Kalter S. S., Schidlovsky G., Peterson W. D., Jr, Daniel M. D. Biologic and antigenic characteristics of Epstein-Barr virus-related Herpesviruses of chimpanzees and baboons. Int J Cancer. 1977 Sep 15;20(3):448–459. doi: 10.1002/ijc.2910200318. [DOI] [PubMed] [Google Scholar]
- Gerber P., Pritchett R. F., Kieff E. D. Antigens and DNA of a chimpanzee agent related to Epstein-Barr virus. J Virol. 1976 Sep;19(3):1090–1099. doi: 10.1128/jvi.19.3.1090-1099.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gerber P., Rosenblum E. N. The incidence of complement-fixing antibodies to herpes simplex and herpes-like viruses in man and rhesus monkeys. Proc Soc Exp Biol Med. 1968 Jun;128(2):541–546. doi: 10.3181/00379727-128-33061. [DOI] [PubMed] [Google Scholar]
- Given D., Kieff E. DNA of Epstein-Barr virus. IV. Linkage map of restriction enzyme fragments of the B95-8 and W91 strains of Epstein-Barr Virus. J Virol. 1978 Nov;28(2):524–542. doi: 10.1128/jvi.28.2.524-542.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Given D., Kieff E. DNA of Epstein-Barr virus. VI. Mapping of the internal tandem reiteration. J Virol. 1979 Aug;31(2):315–324. doi: 10.1128/jvi.31.2.315-324.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Given D., Yee D., Griem K., Kieff E. DNA of Epstein-Barr virus. V. Direct repeats of the ends of Epstein-Barr virus DNA. J Virol. 1979 Jun;30(3):852–862. doi: 10.1128/jvi.30.3.852-862.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goldman M., Landon J. C., Reisher J. I. Fluorescent antibody and gel diffusion reactions of human and chimpanzee sera with cells cultured from Burkitt tumors and normal chimpanzee blood. Cancer Res. 1968 Dec;28(12):2489–2495. [PubMed] [Google Scholar]
- Hayward S. D., Nogee L., Hayward G. S. Organization of repeated regions within the Epstein-Barr virus DNA molecule. J Virol. 1980 Jan;33(1):507–521. doi: 10.1128/jvi.33.1.507-521.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Heller M., Gerber P., Kieff E. Herpesvirus papio DNA is similar in organization to Epstein-Barr virus DNA. J Virol. 1981 Feb;37(2):698–709. doi: 10.1128/jvi.37.2.698-709.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kieff E., Given D., Powell A. L., King W., Dambaugh T., Raab-Traub N. Epstein-Barr virus: structure of the viral DNA and analysis of viral RNA in infected cells. Biochim Biophys Acta. 1979 Nov 30;560(3):355–373. doi: 10.1016/0304-419x(79)90009-x. [DOI] [PubMed] [Google Scholar]
- Kieff E., Hoyer B., Bachenheimer S., Roizman B. Genetic relatedness of type 1 and type 2 herpes simplex viruses. J Virol. 1972 May;9(5):738–745. doi: 10.1128/jvi.9.5.738-745.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kintner C. R., Sugden B. The structure of the termini of the DNA of Epstein-Barr virus. Cell. 1979 Jul;17(3):661–671. doi: 10.1016/0092-8674(79)90273-3. [DOI] [PubMed] [Google Scholar]
- Knipe D. M., Ruyechan W. T., Roizman B., Halliburton I. W. Molecular genetics of herpes simplex virus: demonstration of regions of obligatory and nonobligatory identity within diploid regions of the genome by sequence replacement and insertion. Proc Natl Acad Sci U S A. 1978 Aug;75(8):3896–3900. doi: 10.1073/pnas.75.8.3896. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Landon J. C., Ellis L. B., Zeve V. H., Fabrizio D. P. Herpes-type virus in cultured leukocytes from chimpanzees. J Natl Cancer Inst. 1968 Jan;40(1):181–192. [PubMed] [Google Scholar]
- Lee Y. S., Tanaka A., Lau R. Y., Nonoyama M., Rabin H. Linkage map of the fragments of herpesvirus papio DNA. J Virol. 1981 Feb;37(2):710–720. doi: 10.1128/jvi.37.2.710-720.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Levy J. A., Levy S. B., Hirshaut Y., Kafuko G., Prince A. Presence of EBV antibodies in sera from wild chimpanzees. Nature. 1971 Oct 22;233(5321):559–560. doi: 10.1038/233559a0. [DOI] [PubMed] [Google Scholar]
- Morse L. S., Pereira L., Roizman B., Schaffer P. A. Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants. J Virol. 1978 May;26(2):389–410. doi: 10.1128/jvi.26.2.389-410.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Neubauer R. H., Rabin H., Strnad B. C., Nonoyama M., Nelson-Rees W. A. Establishment of a lymphoblastoid cell line and isolation of an Epstein-Barr-related virus of gorilla origin. J Virol. 1979 Sep;31(3):845–848. doi: 10.1128/jvi.31.3.845-848.1979. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ohno S., Luka J., Falk L., Klein G. Detection of a nuclear, EBNA-type antigen in apparently EBNA-negative Herpesvirus papio (HVP)-transformed lymphoid lines by the acid-fixed nuclear binding technique. Int J Cancer. 1977 Dec 15;20(6):941–946. doi: 10.1002/ijc.2910200618. [DOI] [PubMed] [Google Scholar]
- Raab-Traub N., Dambaugh T., Kieff E. DNA of Epstein-Barr virus VIII: B95-8, the previous prototype, is an unusual deletion derivative. Cell. 1980 Nov;22(1 Pt 1):257–267. doi: 10.1016/0092-8674(80)90173-7. [DOI] [PubMed] [Google Scholar]
- Reedman B. M., Klein G. Cellular localization of an Epstein-Barr virus (EBV)-associated complement-fixing antigen in producer and non-producer lymphoblastoid cell lines. Int J Cancer. 1973 May;11(3):499–520. doi: 10.1002/ijc.2910110302. [DOI] [PubMed] [Google Scholar]
- Rymo L., Forsblom S. Cleavage of Epstein-Barr virus DNA by restriction endonucleases EcoRI, HindIII and BamI. Nucleic Acids Res. 1978 Apr;5(4):1387–1402. doi: 10.1093/nar/5.4.1387. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Southern E. M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J Mol Biol. 1975 Nov 5;98(3):503–517. doi: 10.1016/s0022-2836(75)80083-0. [DOI] [PubMed] [Google Scholar]
- Stevens D. A., Pry T. W., Blackham E. A., Manaker R. A. Comparison of antigens from human and chimpanzee herpes-type virus-infected hemic cell lines. Proc Soc Exp Biol Med. 1970 Feb;133(2):678–683. doi: 10.3181/00379727-133-34543. [DOI] [PubMed] [Google Scholar]
- Wilkie N. M., Stow N. D., Marsden H. S., Preston V., Cortini R., Timbury M. C., Subak-Sharpe J. H. Physical mapping of herpes simplex virus-coded functions and polypeptides by marker rescue and analysis of HSV-1/HSV-2 intertypic recombinants. IARC Sci Publ. 1978;(24 Pt 1):11–31. [PubMed] [Google Scholar]
- Williams J., Grodzicker T., Sharp P., Sambrook J. Adenovirus recombination: physical mapping of crossover events. Cell. 1975 Feb;4(2):113–119. doi: 10.1016/0092-8674(75)90117-8. [DOI] [PubMed] [Google Scholar]
- Yanofsky C., Li S. S., Horn V., Rowe J. Structure and properties of a hybrid tryptophan synthetase of alpha chain produced by genetic exchange between Escherichia coli and Salmonella typhimurium. Proc Natl Acad Sci U S A. 1977 Jan;74(1):286–290. doi: 10.1073/pnas.74.1.286. [DOI] [PMC free article] [PubMed] [Google Scholar]