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. 1981 Mar;37(3):893–898. doi: 10.1128/jvi.37.3.893-898.1981

Postinfection control in T4 bacteriophage infection: inhibition of the rep function.

K Ebisuzaki, S B Jellie
PMCID: PMC171085  PMID: 6112279

Abstract

We suggest that the general mechanism by which T4 phage turns off host macromolecular synthesis involves specific phage proteins which react with key components in the synthetic pathway. Support for this mechanism exists for the inhibition of host RNA synthesis. Here we note that the host rep function was inhibited after T4 phage infection. Since rep functions are known to be involved in host DNA replication, inhibition of rep might alter the course of host DNA replication.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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