Skip to main content
NCBI home page
Clinical and Experimental Immunology logoLink to Clinical and Experimental Immunology
. 1971 Jan;8(1):63–68.

Immunoglobulin levels in pneumonia

M E Schonell
PMCID: PMC1712900  PMID: 4099988

Abstract

Serum immunoglobulin levels were measured by radial immunodiffusion in thirty patients with pneumonia and in thirty healthy controls. In pneumonia the mean IgG level increased during the course of the illness. During convalescence the mean IgM and IgG levels were higher in patients than in controls. The results of immunoglobulin estimations were correlated with the results of aetiological investigations. Patients with M. pneumoniae infections showed a significant rise in IgM concentration which may be specific for respiratory infections associated with this organism.

Full text

PDF
63

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allansmith M., McClellan B., Butterworth M. Evidence for the independence of human immunoglobulin class levels. Immunology. 1967 Nov;13(5):483–488. [PMC free article] [PubMed] [Google Scholar]
  2. BRADSTREET C. M., TAYLOR C. E. Technique of complementfixation test applicable to the diagnosis of virus diseases. Mon Bull Minist Health Public Health Lab Serv. 1962 May;21:96–104. [PubMed] [Google Scholar]
  3. Calder M. A., McHardy V. U., Schonell M. E. Importance of pneumococcal typing in pneumonia. Lancet. 1970 Jan 3;1(7636):5–7. doi: 10.1016/s0140-6736(70)90521-0. [DOI] [PubMed] [Google Scholar]
  4. Feizi T. Cold agglutinins, the direct coombs' test and serum immunoglobulins in Mycoplasma pneumoniae infection. Ann N Y Acad Sci. 1967 Jul 28;143(1):801–812. doi: 10.1111/j.1749-6632.1967.tb27728.x. [DOI] [PubMed] [Google Scholar]
  5. Mancini G., Carbonara A. O., Heremans J. F. Immunochemical quantitation of antigens by single radial immunodiffusion. Immunochemistry. 1965 Sep;2(3):235–254. doi: 10.1016/0019-2791(65)90004-2. [DOI] [PubMed] [Google Scholar]
  6. McKelvey E. M., Fahey J. L. Immunoglobulin changes in disease: quantitation on the basis of heavy polypeptide chains, IgG (gammaG), IgA (gammaA), and IgM (gammaM), and of light polypeptide chains, type K (I) and type L (II). J Clin Invest. 1965 Nov;44(11):1778–1787. doi: 10.1172/JCI105285. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. ROSEN F. S., BOUGAS J. A. ACQUIRED DYSGAMMAGLOBULINEMIA: ELEVATION OF THE 19S GAMMA GLOBULIN AND DEFICIENCY OF THE 7S GAMMA GLOBULIN IN A WOMAN WITH CHRONIC PROGRESSIVE BRONCHIECTASIS. N Engl J Med. 1963 Dec 19;269:1336–1340. doi: 10.1056/NEJM196312192692502. [DOI] [PubMed] [Google Scholar]
  8. SELL S., FAHEY J. L. RELATIONSHIP BETWEEN GAMMA-GLOBULIN METABOLISM AND LOW SERUM GAMMA-GLOBULIN IN GERMFREE MICE. J Immunol. 1964 Jul;93:81–87. [PubMed] [Google Scholar]
  9. SUHS R. H., DOWLING H. F., JACKSON G. G. HYPOGAMMAGLOBULINEMIA WITH CHRONIC BRONCHITIS OR BRONCHIECTASIS; TREATMENT OF FIVE PATIENTS WITH LONG-TERM ANTIBIOTIC THERAPY. Arch Intern Med. 1965 Jul;116:29–38. doi: 10.1001/archinte.1965.03870010031006. [DOI] [PubMed] [Google Scholar]
  10. Schonell M. E., Gray W., Moffat M. A., Calder M. A., Stewart S. M. The relationship between the aetiology of pneumonia in adults and certain clinical and radiographic findings. Br J Dis Chest. 1969 Jul;63(3):140–149. doi: 10.1016/s0007-0971(69)80011-2. [DOI] [PubMed] [Google Scholar]
  11. Stewart S. M., Chowdray J. E. Isolation of mycoplasmas from the human respiratory tract. J Pathol Bacteriol. 1968 Apr;95(2):580–586. doi: 10.1002/path.1700950239. [DOI] [PubMed] [Google Scholar]

Articles from Clinical and Experimental Immunology are provided here courtesy of British Society for Immunology

RESOURCES