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. 1971 Jan;8(1):37–43.

Studies on lymphocyte and monocyte function in chronic mucotaneous candidiasis

L S Goldberg, R Bluestone, E V Barnett, J W Landau
PMCID: PMC1712909  PMID: 5099755

Abstract

Lymphocyte and monocyte function was studied in an anergic patient with chronic mucocutaneous candidiasis. Her lymphocytes responded in vitro to phytohaemagglutinin, but not to Candida albicans antigen. However, when the lymphocytes were cultured in the presence of C. albicans, they produced migration inhibitory factor (MIF) capable of inhibiting either human or guinea-pig monocytes. Monocytes isolated from the patient's blood were also shown to have intact IgG receptors, a system perhaps analogous to cytophilic antibody. These findings indicate that the anergic state present in our patient with mucocutaneous candidiasis cannot be attributed to a failure of antigen recognition or to a defect in MIF production.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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