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. 1972 Apr;10(4):649–659.

Thymus origin of lymphocytes reacting and stimulating reaction in mixed lymphocyte cultures-studies in the rat

B P Maclaurin
PMCID: PMC1713118  PMID: 5034246

Abstract

Mixed lymphocyte cultures between pairs of allogeneic cell suspensions from rat thymus of one strain versus thymus, lymph node, spleen or bone marrow from a histo-incompatible strain, have shown a decreasing gradient of stimulation capacity. After complete neonatal thymectomy 6 weeks previously, lymph-node lymphocytes are shown to have diminished or absent capacity to stimulate allogeneic rat thymocytes in mixed culture. It it concluded that thymus-derived lymphocytes appear to be required both for stimulation as well as for reaction in the mixed lymphocyte test.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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