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. 1981 Sep;39(3):855–860. doi: 10.1128/jvi.39.3.855-860.1981

DNA gyrase inhibitors block development of Bacillus subtilis bacteriophage SP01.

J C Alonso, A N Sarachu, O Grau
PMCID: PMC171318  PMID: 6270354

Abstract

SP01 development was inhibited by nalidixic acid and novobiocin in the sensitive host Bacillus subtilis 168M. Inhibition by novobiocin was prevented by a Novr mutation in the cellular DNA gyrase gene. Nalidixic acid inhibition persisted in hosts carrying a Nalr gyrase, but could be overcome by phage mutation. We conclude that SP01 requires for its development subunit B of the host DNA gyrase, but replaces or modifies subunit A.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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