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. 1989 Feb;33(2):239–241. doi: 10.1128/aac.33.2.239

Fleroxacin resistance in Escherichia coli.

J S Chapman 1, A Bertasso 1, N H Georgopapadakou 1
PMCID: PMC171465  PMID: 2541657

Abstract

Spontaneous fleroxacin-resistant mutants of Escherichia coli K-12 were isolated at a frequency of 10(-10) to 10(-11) mutants per CFU plated. All mutants exhibited quinolone-resistant replicative DNA biosynthesis, and 4 of 11 mutants also had decreased amounts of OmpF or OmpC porin. None of the mutants had changes solely in porin proteins.

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Selected References

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