Abstract
Seventy-four cefoxitin-resistant Bacteroides fragilis group isolates were tested by the serial twofold agar dilution method for susceptibility to imipenem and other agents in medium with and without 5% sheep blood. Imipenem (MIC for 90% of strains tested, 1 microgram/ml) and metronidazole (MIC for 90% of strains tested, 2 micrograms/ml) were the two most active agents. The addition of 5% sheep blood to the medium had little or no effect on the activity of the antibiotics tested.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Brown W. J. National Committee for Clinical Laboratory Standards agar dilution susceptibility testing of anaerobic gram-negative bacteria. Antimicrob Agents Chemother. 1988 Mar;32(3):385–390. doi: 10.1128/aac.32.3.385. [DOI] [PMC free article] [PubMed] [Google Scholar]
- File T. M., Jr, Thomson R. B., Jr, Tan J. S., Salstrom S. J., Jacobs G. A., Johnson L., Tan L. In vitro susceptibility of the Bacteroides fragilis group in community hospitals. Diagn Microbiol Infect Dis. 1986 Nov;5(4):317–322. doi: 10.1016/0732-8893(86)90035-0. [DOI] [PubMed] [Google Scholar]
- Jones R. N., Barry A. L., Aldridge K. E., Gerlach E. H. Comparative antimicrobial activity of aminothiazolyl methoxyimino cephalosporins against anaerobic bacteria, including 100 cefoxitin-resistant isolates. Diagn Microbiol Infect Dis. 1987 Nov;8(3):157–163. doi: 10.1016/0732-8893(87)90166-0. [DOI] [PubMed] [Google Scholar]
- O'Keefe J. P., Venezio F. R., DiVincenzo C. A., Shatzer K. L. Activity of newer beta-lactam agents against clinical isolates of Bacteroides fragilis and other Bacteroides species. Antimicrob Agents Chemother. 1987 Dec;31(12):2002–2004. doi: 10.1128/aac.31.12.2002. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tally F. P., Cuchural G. J., Jacobus N. V., Gorbach S. L., Aldridge K. E., Cleary T. J., Finegold S. M., Hill G. B., Iannini P. B., McCloskey R. V. Susceptibility of the Bacteroides fragilis group in the United States in 1981. Antimicrob Agents Chemother. 1983 Apr;23(4):536–540. doi: 10.1128/aac.23.4.536. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Wexler H. M., Finegold S. M. Antimicrobial resistance in Bacteroides. J Antimicrob Chemother. 1987 Feb;19(2):143–146. doi: 10.1093/jac/19.2.143. [DOI] [PubMed] [Google Scholar]