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. 1988 Jan;42(1):60–65.

A new approach in recognition of heterochromatic regions of human chromosomes by means of restriction endonucleases.

A Babu 1, A K Agarwal 1, R S Verma 1
PMCID: PMC1715309  PMID: 2827464

Abstract

The heteromorphisms of C-band regions of human chromosomes are evaluated by means of restriction endonucleases AluI, DdeI, MboI, and RsaI. Every chromosome exhibits heteromorphic markers of the C-band regions except chromosome 8. Each enzyme was found to be highly characteristic in its staining profile, a result that clearly suggests the diversity of heterochromatin. The inherent C-band-region heterochromatin variability that is revealed by these enzymes provides a valuable tool in identifying markers as compared with other previously described techniques.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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