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Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1990 Jan;34(1):156–158. doi: 10.1128/aac.34.1.156

Diverse potential of beta-lactamase inhibitors to induce class I enzymes.

D A Weber 1, C C Sanders 1
PMCID: PMC171539  PMID: 2327752

Abstract

The ability of various beta-lactamase inhibitors to induce class I beta-lactamases was assessed. Clavulanate was the most active compound, inducing Morganella morganii, Aeromonas caviae, and Enterobacter aerogenes over a broad concentration range and Citrobacter freundii, Pseudomonas aeruginosa, and Serratia marcescens at high concentrations. Disk approximation tests paralleled these results, with clavulanate, but not sulbactam or tazobactam, antagonizing the activity of several beta-lactams against these organisms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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