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. 1989 Jan;44(1):38–40.

Linkage analysis of chromosome 17 markers in British and South African families with neurofibromatosis type 1

C G P Mathew, K Thorpe, D F Easton, K S Chin, D Jadayel, M Ponder, G Moore, C E Wallis, C P Slater, G De Jong, P O'Connell, R White, D Barker, B A J Ponder
PMCID: PMC1715463  PMID: 2491780

Abstract

Nine markers from the pericentromeric region of chromosome 17 were typed in 16 British and five South African families with neurofibromatosis type 1 (NF1). The markers–p17H8, pHHH202, and EW204–were linked to NF1 at recombination fractions <1%. No evidence of locus heterogeneity was detected. Inspection of recombinant events in families informative for several markers suggests that the NF1 gene is located between the markers EW301 (cen-p11.2) and EW206 (cen-q12) and possibly distal to pHHH202 (q11.2-q12).

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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