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American Journal of Human Genetics logoLink to American Journal of Human Genetics
. 1989 Jun;44(6):890–893.

Human pregnancy-specific beta 1-glycoproteins are coded within chromosome 19.

T R Barnett 1, W Pickle 2nd 1, P M Rae 1, J Hart 1, M Kamarck 1, J Elting 1
PMCID: PMC1715672  PMID: 2786334

Abstract

We have isolated and characterized cDNAs that code for apoproteins having amino acid sequences highly similar to pregnancy-specific beta 1-glycoproteins (PS beta G). cDNAs coding for PS beta Gs, as well as the cDNA clone reported here, are members of the carcinoembryonic antigen (CEA) gene family. The previous localization of CEA-related genes to human chromosome 19, and the high level of DNA sequence conservation in the CEA family, suggested that the PS beta G genes are also located on this chromosome. We demonstrate here that chromosome 19 is indeed the site of PS beta G sequences. Our finding is in contrast to the recently reported indication that pregnancy-specific glycoproteins are encoded in chromosomes X and 6.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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