Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 1997 Dec;77(6):524–525. doi: 10.1136/adc.77.6.524

Early onset of diabetic nephropathy

J Francis 1, S Rose 1, F Raafat 1, D Milford 1
PMCID: PMC1717409  PMID: 9496190

Abstract





A 12 year old Asian girl with a four year history of poorly controlled insulin dependent diabetes mellitus developed overt diabetic nephropathy. There were no clinical features of Rabson-Mendenhall syndrome. Screening for microalbuminuria would have identified incipient diabetic nephropathy and highlighted the importance of good glycaemic control. Although screening for microalbuminuria is recommended after five years from diagnosis, it may be appropriate to undertake this annually in those with poor glycaemic control.



Full Text

The Full Text of this article is available as a PDF (113.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Campbell F. M. Microalbuminuria and nephropathy in insulin dependent diabetes mellitus. Arch Dis Child. 1995 Jul;73(1):4–7. doi: 10.1136/adc.73.1.4. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Coonrod B. A., Ellis D., Becker D. J., Bunker C. H., Kelsey S. F., Lloyd C. E., Drash A. L., Kuller L. H., Orchard T. J. Predictors of microalbuminuria in individuals with IDDM. Pittsburgh Epidemiology of Diabetes Complications Study. Diabetes Care. 1993 Oct;16(10):1376–1383. doi: 10.2337/diacare.16.10.1376. [DOI] [PubMed] [Google Scholar]
  3. DeClue T. J., Campos A. Diabetic nephropathy in a prepubertal diabetic female. J Pediatr Endocrinol. 1994 Jan-Mar;7(1):43–46. doi: 10.1515/jpem.1994.7.1.43. [DOI] [PubMed] [Google Scholar]
  4. Quattrin T., Waz W. R., Duffy L. C., Sheldon M. W., Campos S. P., Albini C. H., Feld L. G. Microalbuminuria in an adolescent cohort with insulin-dependent diabetes mellitus. Clin Pediatr (Phila) 1995 Jan;34(1):12–17. doi: 10.1177/000992289503400103. [DOI] [PubMed] [Google Scholar]
  5. Shield J. P., Hunt L. P., Karachaliou F., Karavanaki K., Baum J. D. Is microalbuminuria progressive? Arch Dis Child. 1995 Dec;73(6):512–514. doi: 10.1136/adc.73.6.512. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Throckmorton D. C., Brogden A. P., Min B., Rasmussen H., Kashgarian M. PDGF and TGF-beta mediate collagen production by mesangial cells exposed to advanced glycosylation end products. Kidney Int. 1995 Jul;48(1):111–117. doi: 10.1038/ki.1995.274. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES