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. 1998 Jun;78(6):524–530. doi: 10.1136/adc.78.6.524

Determinants of axial and peripheral bone mass in Chinese adolescents

J Cheng 1, S Leung 1, W Lee 1, J Lau 1, N Maffulli 1, A Cheung 1, K Chan 1
PMCID: PMC1717607  PMID: 9713007

Abstract

OBJECTIVE—To determine the relation of puberty, physical activity, physical fitness, and calcium intake with bone mineral content (BMC) of the distal radius, and on bone mineral density (BMD) of the L2 to L4 vertebrae in a group of healthy Chinese adolescents.
DESIGN—Cross sectional survey.
SUBJECTS—A group of 179 healthy Chinese adolescents (92 boys and 87 girls) aged 12 to 13 years enrolled in the first year of the Tii Junior High School in Shatin, Hong Kong. Ninety four of the pupils enrolled were in the physical education major class (PE), and the other 85 were in the art major class (ARTS).
MAIN OUTCOME MEASURES—Correlation of BMC of the distal radius and BMD of the L2 to L4 vertebrae with level of physical activity, physical fitness (isometric and isokinetic), muscle strength of the upper and lower limb, and calcium intake.
RESULTS—BMC of the distal radius and BMD of the L2 to L4 vertebrae were significantly positively correlated. Univariate and regression analysis showed that age, pubertal staging, physical fitness, and muscle strength were significantly associated with bone mass in a positive way. Calcium intake and type of sport practised did not exert a significant influence on BMC of the distal radius and BMD of the L2 to L4 vertebrae in boys. The results for the BMD of the L2 to L4 vertebrae were similar in girls and boys; however, in girls, the BMC of the distal radius had a negative correlation with calcium intake. Physical fitness was a significant positive predictor of BMD of the L2 to L4 vertebrae.
CONCLUSIONS—Among Chinese adolescents bone mass was positively influenced by certain measures of physical fitness as well as by age, weight, and pubertal stage.



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Selected References

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  1. Anderson J. J., Metz J. A. Contributions of dietary calcium and physical activity to primary prevention of osteoporosis in females. J Am Coll Nutr. 1993 Aug;12(4):378–383. doi: 10.1080/07315724.1993.10718326. [DOI] [PubMed] [Google Scholar]
  2. Blimkie C. J., Rice S., Webber C. E., Martin J., Levy D., Gordon C. L. Effects of resistance training on bone mineral content and density in adolescent females. Can J Physiol Pharmacol. 1996 Sep;74(9):1025–1033. [PubMed] [Google Scholar]
  3. Boot A. M., de Ridder M. A., Pols H. A., Krenning E. P., de Muinck Keizer-Schrama S. M. Bone mineral density in children and adolescents: relation to puberty, calcium intake, and physical activity. J Clin Endocrinol Metab. 1997 Jan;82(1):57–62. doi: 10.1210/jcem.82.1.3665. [DOI] [PubMed] [Google Scholar]
  4. Dequeker J., Nijs J., Verstraeten A., Geusens P., Gevers G. Genetic determinants of bone mineral content at the spine and radius: a twin study. Bone. 1987;8(4):207–209. doi: 10.1016/8756-3282(87)90166-9. [DOI] [PubMed] [Google Scholar]
  5. Gilsanz V., Roe T. F., Mora S., Costin G., Goodman W. G. Changes in vertebral bone density in black girls and white girls during childhood and puberty. N Engl J Med. 1991 Dec 5;325(23):1597–1600. doi: 10.1056/NEJM199112053252302. [DOI] [PubMed] [Google Scholar]
  6. Krall E. A., Dawson-Hughes B. Heritable and life-style determinants of bone mineral density. J Bone Miner Res. 1993 Jan;8(1):1–9. doi: 10.1002/jbmr.5650080102. [DOI] [PubMed] [Google Scholar]
  7. Lau E. M., Woo J., Leung P. C., Swaminathan R., Leung D. The effects of calcium supplementation and exercise on bone density in elderly Chinese women. Osteoporos Int. 1992 Jul;2(4):168–173. doi: 10.1007/BF01623922. [DOI] [PubMed] [Google Scholar]
  8. Lee W. T., Leung S. S., Lui S. S., Lau J. Relationship between long-term calcium intake and bone mineral content of children aged from birth to 5 years. Br J Nutr. 1993 Jul;70(1):235–248. doi: 10.1079/bjn19930120. [DOI] [PubMed] [Google Scholar]
  9. Lee W. T., Leung S. S., Wang S. H., Xu Y. C., Zeng W. P., Lau J., Oppenheimer S. J., Cheng J. C. Double-blind, controlled calcium supplementation and bone mineral accretion in children accustomed to a low-calcium diet. Am J Clin Nutr. 1994 Nov;60(5):744–750. doi: 10.1093/ajcn/60.5.744. [DOI] [PubMed] [Google Scholar]
  10. Li R. C., Wu Y., Maffulli N., Chan K. M., Chan J. L. Eccentric and concentric isokinetic knee flexion and extension: a reliability study using the Cybex 6000 dynamometer. Br J Sports Med. 1996 Jun;30(2):156–160. doi: 10.1136/bjsm.30.2.156. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Lloyd T., Andon M. B., Rollings N., Martel J. K., Landis J. R., Demers L. M., Eggli D. F., Kieselhorst K., Kulin H. E. Calcium supplementation and bone mineral density in adolescent girls. JAMA. 1993 Aug 18;270(7):841–844. [PubMed] [Google Scholar]
  12. Luckey M. M., Meier D. E., Mandeli J. P., DaCosta M. C., Hubbard M. L., Goldsmith S. J. Radial and vertebral bone density in white and black women: evidence for racial differences in premenopausal bone homeostasis. J Clin Endocrinol Metab. 1989 Oct;69(4):762–770. doi: 10.1210/jcem-69-4-762. [DOI] [PubMed] [Google Scholar]
  13. Maffulli N., King J. B. Effects of physical activity on some components of the skeletal system. Sports Med. 1992 Jun;13(6):393–407. doi: 10.2165/00007256-199213060-00003. [DOI] [PubMed] [Google Scholar]
  14. Menkes A., Mazel S., Redmond R. A., Koffler K., Libanati C. R., Gundberg C. M., Zizic T. M., Hagberg J. M., Pratley R. E., Hurley B. F. Strength training increases regional bone mineral density and bone remodeling in middle-aged and older men. J Appl Physiol (1985) 1993 May;74(5):2478–2484. doi: 10.1152/jappl.1993.74.5.2478. [DOI] [PubMed] [Google Scholar]
  15. Nelson D. A., Simpson P. M., Johnson C. C., Barondess D. A., Kleerekoper M. The accumulation of whole body skeletal mass in third- and fourth-grade children: effects of age, gender, ethnicity, and body composition. Bone. 1997 Jan;20(1):73–78. doi: 10.1016/s8756-3282(96)00312-2. [DOI] [PubMed] [Google Scholar]
  16. Riggs B. L., Wahner H. W., Dunn W. L., Mazess R. B., Offord K. P., Melton L. J., 3rd Differential changes in bone mineral density of the appendicular and axial skeleton with aging: relationship to spinal osteoporosis. J Clin Invest. 1981 Feb;67(2):328–335. doi: 10.1172/JCI110039. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Rubin K., Schirduan V., Gendreau P., Sarfarazi M., Mendola R., Dalsky G. Predictors of axial and peripheral bone mineral density in healthy children and adolescents, with special attention to the role of puberty. J Pediatr. 1993 Dec;123(6):863–870. doi: 10.1016/s0022-3476(05)80381-6. [DOI] [PubMed] [Google Scholar]
  18. Sievänen H., Oja P., Vuori I. Precision of dual-energy x-ray absorptiometry in determining bone mineral density and content of various skeletal sites. J Nucl Med. 1992 Jun;33(6):1137–1142. [PubMed] [Google Scholar]
  19. Snow-Harter C., Bouxsein M. L., Lewis B. T., Carter D. R., Marcus R. Effects of resistance and endurance exercise on bone mineral status of young women: a randomized exercise intervention trial. J Bone Miner Res. 1992 Jul;7(7):761–769. doi: 10.1002/jbmr.5650070706. [DOI] [PubMed] [Google Scholar]
  20. Steele M. F., Mattox J. W. Correlation of arm-span and height in young women of two races. Ann Hum Biol. 1987 Sep-Oct;14(5):445–447. doi: 10.1080/03014468700009261. [DOI] [PubMed] [Google Scholar]
  21. Theintz G., Buchs B., Rizzoli R., Slosman D., Clavien H., Sizonenko P. C., Bonjour J. P. Longitudinal monitoring of bone mass accumulation in healthy adolescents: evidence for a marked reduction after 16 years of age at the levels of lumbar spine and femoral neck in female subjects. J Clin Endocrinol Metab. 1992 Oct;75(4):1060–1065. doi: 10.1210/jcem.75.4.1400871. [DOI] [PubMed] [Google Scholar]
  22. Vico L., Prallet B., Chappard D., Pallot-Prades B., Pupier R., Alexandre C. Contributions of chronological age, age at menarche and menopause and of anthropometric parameters to axial and peripheral bone densities. Osteoporos Int. 1992 May;2(3):153–158. doi: 10.1007/BF01623823. [DOI] [PubMed] [Google Scholar]

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