Full Text
The Full Text of this article is available as a PDF (84.8 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Armstrong J. F., Pritchard-Jones K., Bickmore W. A., Hastie N. D., Bard J. B. The expression of the Wilms' tumour gene, WT1, in the developing mammalian embryo. Mech Dev. 1993 Jan;40(1-2):85–97. doi: 10.1016/0925-4773(93)90090-k. [DOI] [PubMed] [Google Scholar]
- Barbaux S., Niaudet P., Gubler M. C., Grünfeld J. P., Jaubert F., Kuttenn F., Fékété C. N., Souleyreau-Therville N., Thibaud E., Fellous M. Donor splice-site mutations in WT1 are responsible for Frasier syndrome. Nat Genet. 1997 Dec;17(4):467–470. doi: 10.1038/ng1297-467. [DOI] [PubMed] [Google Scholar]
- Bardeesy N., Zabel B., Schmitt K., Pelletier J. WT1 mutations associated with incomplete Denys-Drash syndrome define a domain predicted to behave in a dominant-negative fashion. Genomics. 1994 Jun;21(3):663–664. doi: 10.1006/geno.1994.1333. [DOI] [PubMed] [Google Scholar]
- Beckwith J. B., Kiviat N. B., Bonadio J. F. Nephrogenic rests, nephroblastomatosis, and the pathogenesis of Wilms' tumor. Pediatr Pathol. 1990;10(1-2):1–36. doi: 10.3109/15513819009067094. [DOI] [PubMed] [Google Scholar]
- Beckwith J. B. Precursor lesions of Wilms tumor: clinical and biological implications. Med Pediatr Oncol. 1993;21(3):158–168. doi: 10.1002/mpo.2950210303. [DOI] [PubMed] [Google Scholar]
- Borel F., Barilla K. C., Hamilton T. B., Iskandar M., Romaniuk P. J. Effects of Denys-Drash syndrome point mutations on the DNA binding activity of the Wilms' tumor suppressor protein WT1. Biochemistry. 1996 Sep 17;35(37):12070–12076. doi: 10.1021/bi960758o. [DOI] [PubMed] [Google Scholar]
- Breslow N., Beckwith J. B., Ciol M., Sharples K. Age distribution of Wilms' tumor: report from the National Wilms' Tumor Study. Cancer Res. 1988 Mar 15;48(6):1653–1657. [PubMed] [Google Scholar]
- Brown K. W., Wilmore H. P., Watson J. E., Mott M. G., Berry P. J., Maitland N. J. Low frequency of mutations in the WT1 coding region in Wilms' tumor. Genes Chromosomes Cancer. 1993 Oct;8(2):74–79. doi: 10.1002/gcc.2870080203. [DOI] [PubMed] [Google Scholar]
- Bruening W., Pelletier J. A non-AUG translational initiation event generates novel WT1 isoforms. J Biol Chem. 1996 Apr 12;271(15):8646–8654. doi: 10.1074/jbc.271.15.8646. [DOI] [PubMed] [Google Scholar]
- Call K. M., Glaser T., Ito C. Y., Buckler A. J., Pelletier J., Haber D. A., Rose E. A., Kral A., Yeger H., Lewis W. H. Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell. 1990 Feb 9;60(3):509–520. doi: 10.1016/0092-8674(90)90601-a. [DOI] [PubMed] [Google Scholar]
- Coppes M. J., Campbell C. E., Williams B. R. The role of WT1 in Wilms tumorigenesis. FASEB J. 1993 Jul;7(10):886–895. doi: 10.1096/fasebj.7.10.8393819. [DOI] [PubMed] [Google Scholar]
- Coppes M. J., de Kraker J., van Dijken P. J., Perry H. J., Delemarre J. F., Tournade M. F., Lemerle J., Voûte P. A. Bilateral Wilms' tumor: long-term survival and some epidemiological features. J Clin Oncol. 1989 Mar;7(3):310–315. doi: 10.1200/JCO.1989.7.3.310. [DOI] [PubMed] [Google Scholar]
- Denys P., Malvaux P., Van Den Berghe H., Tanghe W., Proesmans W. Association d'un syndrome anatomo-pathologique de pseudohermaphrodisme masculin, d'une tumeur de Wilms, d'une nephropathie parenchymateuse et d'un mosaicisme XX/XY. Arch Fr Pediatr. 1967 Aug-Sep;24(7):729–739. [PubMed] [Google Scholar]
- Drash A., Sherman F., Hartmann W. H., Blizzard R. M. A syndrome of pseudohermaphroditism, Wilms' tumor, hypertension, and degenerative renal disease. J Pediatr. 1970 Apr;76(4):585–593. doi: 10.1016/s0022-3476(70)80409-7. [DOI] [PubMed] [Google Scholar]
- Eddy A. A., Mauer S. M. Pseudohermaphroditism, glomerulopathy, and Wilms tumor (Drash syndrome): frequency in end-stage renal failure. J Pediatr. 1985 Apr;106(4):584–587. doi: 10.1016/s0022-3476(85)80076-7. [DOI] [PubMed] [Google Scholar]
- FRASIER S. D., BASHORE R. A., MOSIER H. D. GONADOBLASTOMA ASSOCIATED WITH PURE GONADAL DYSGENESIS IN MONOZYGOUS TWINS. J Pediatr. 1964 May;64:740–745. doi: 10.1016/s0022-3476(64)80622-3. [DOI] [PubMed] [Google Scholar]
- Francke U., Holmes L. B., Atkins L., Riccardi V. M. Aniridia-Wilms' tumor association: evidence for specific deletion of 11p13. Cytogenet Cell Genet. 1979;24(3):185–192. doi: 10.1159/000131375. [DOI] [PubMed] [Google Scholar]
- Gessler M., König A., Arden K., Grundy P., Orkin S., Sallan S., Peters C., Ruyle S., Mandell J., Li F. Infrequent mutation of the WT1 gene in 77 Wilms' Tumors. Hum Mutat. 1994;3(3):212–222. doi: 10.1002/humu.1380030307. [DOI] [PubMed] [Google Scholar]
- Gessler M., Poustka A., Cavenee W., Neve R. L., Orkin S. H., Bruns G. A. Homozygous deletion in Wilms tumours of a zinc-finger gene identified by chromosome jumping. Nature. 1990 Feb 22;343(6260):774–778. doi: 10.1038/343774a0. [DOI] [PubMed] [Google Scholar]
- Haber D. A., Sohn R. L., Buckler A. J., Pelletier J., Call K. M., Housman D. E. Alternative splicing and genomic structure of the Wilms tumor gene WT1. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9618–9622. doi: 10.1073/pnas.88.21.9618. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jeanpierre C., Béroud C., Niaudet P., Junien C. Software and database for the analysis of mutations in the human WT1 gene. Nucleic Acids Res. 1998 Jan 1;26(1):271–274. doi: 10.1093/nar/26.1.271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jeanpierre C., Denamur E., Henry I., Cabanis M. O., Luce S., Cécille A., Elion J., Peuchmaur M., Loirat C., Niaudet P. Identification of constitutional WT1 mutations, in patients with isolated diffuse mesangial sclerosis, and analysis of genotype/phenotype correlations by use of a computerized mutation database. Am J Hum Genet. 1998 Apr;62(4):824–833. doi: 10.1086/301806. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kikuchi H., Takata A., Akasaka Y., Fukuzawa R., Yoneyama H., Kurosawa Y., Honda M., Kamiyama Y., Hata J. Do intronic mutations affecting splicing of WT1 exon 9 cause Frasier syndrome? J Med Genet. 1998 Jan;35(1):45–48. doi: 10.1136/jmg.35.1.45. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Klamt B., Koziell A., Poulat F., Wieacker P., Scambler P., Berta P., Gessler M. Frasier syndrome is caused by defective alternative splicing of WT1 leading to an altered ratio of WT1 +/-KTS splice isoforms. Hum Mol Genet. 1998 Apr;7(4):709–714. doi: 10.1093/hmg/7.4.709. [DOI] [PubMed] [Google Scholar]
- Knudson A. G., Jr, Strong L. C. Mutation and cancer: a model for Wilms' tumor of the kidney. J Natl Cancer Inst. 1972 Feb;48(2):313–324. [PubMed] [Google Scholar]
- Kreidberg J. A., Sariola H., Loring J. M., Maeda M., Pelletier J., Housman D., Jaenisch R. WT-1 is required for early kidney development. Cell. 1993 Aug 27;74(4):679–691. doi: 10.1016/0092-8674(93)90515-r. [DOI] [PubMed] [Google Scholar]
- Larsson S. H., Charlieu J. P., Miyagawa K., Engelkamp D., Rassoulzadegan M., Ross A., Cuzin F., van Heyningen V., Hastie N. D. Subnuclear localization of WT1 in splicing or transcription factor domains is regulated by alternative splicing. Cell. 1995 May 5;81(3):391–401. doi: 10.1016/0092-8674(95)90392-5. [DOI] [PubMed] [Google Scholar]
- Little M. H., Williamson K. A., Mannens M., Kelsey A., Gosden C., Hastie N. D., van Heyningen V. Evidence that WT1 mutations in Denys-Drash syndrome patients may act in a dominant-negative fashion. Hum Mol Genet. 1993 Mar;2(3):259–264. doi: 10.1093/hmg/2.3.259. [DOI] [PubMed] [Google Scholar]
- Little M., Holmes G., Bickmore W., van Heyningen V., Hastie N., Wainwright B. DNA binding capacity of the WT1 protein is abolished by Denys-Drash syndrome WT1 point mutations. Hum Mol Genet. 1995 Mar;4(3):351–358. doi: 10.1093/hmg/4.3.351. [DOI] [PubMed] [Google Scholar]
- Little M., Wells C. A clinical overview of WT1 gene mutations. Hum Mutat. 1997;9(3):209–225. doi: 10.1002/(SICI)1098-1004(1997)9:3<209::AID-HUMU2>3.0.CO;2-2. [DOI] [PubMed] [Google Scholar]
- McMaster M. L., Gessler M., Stanbridge E. J., Weissman B. E. WT1 expression alters tumorigenicity of the G401 kidney-derived cell line. Cell Growth Differ. 1995 Dec;6(12):1609–1617. [PubMed] [Google Scholar]
- Moffett P., Bruening W., Nakagama H., Bardeesy N., Housman D., Housman D. E., Pelletier J. Antagonism of WT1 activity by protein self-association. Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11105–11109. doi: 10.1073/pnas.92.24.11105. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Montgomery B. T., Kelalis P. P., Blute M. L., Bergstralh E. J., Beckwith J. B., Norkool P., Green D. M., D'Angio G. J. Extended followup of bilateral Wilms tumor: results of the National Wilms Tumor Study. J Urol. 1991 Aug;146(2 ):514–518. doi: 10.1016/s0022-5347(17)37840-0. [DOI] [PubMed] [Google Scholar]
- Morris J. F., Madden S. L., Tournay O. E., Cook D. M., Sukhatme V. P., Rauscher F. J., 3rd Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus. Oncogene. 1991 Dec;6(12):2339–2348. [PubMed] [Google Scholar]
- Mueller R. F. The Denys-Drash syndrome. J Med Genet. 1994 Jun;31(6):471–477. doi: 10.1136/jmg.31.6.471. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Nachtigal M. W., Hirokawa Y., Enyeart-VanHouten D. L., Flanagan J. N., Hammer G. D., Ingraham H. A. Wilms' tumor 1 and Dax-1 modulate the orphan nuclear receptor SF-1 in sex-specific gene expression. Cell. 1998 May 1;93(3):445–454. doi: 10.1016/s0092-8674(00)81172-1. [DOI] [PubMed] [Google Scholar]
- Pritchard-Jones K., Fleming S., Davidson D., Bickmore W., Porteous D., Gosden C., Bard J., Buckler A., Pelletier J., Housman D. The candidate Wilms' tumour gene is involved in genitourinary development. Nature. 1990 Jul 12;346(6280):194–197. doi: 10.1038/346194a0. [DOI] [PubMed] [Google Scholar]
- Rauscher F. J., 3rd The WT1 Wilms tumor gene product: a developmentally regulated transcription factor in the kidney that functions as a tumor suppressor. FASEB J. 1993 Jul;7(10):896–903. [PubMed] [Google Scholar]
- Schumacher V., Schärer K., Wühl E., Altrogge H., Bonzel K. E., Guschmann M., Neuhaus T. J., Pollastro R. M., Kuwertz-Bröking E., Bulla M. Spectrum of early onset nephrotic syndrome associated with WT1 missense mutations. Kidney Int. 1998 Jun;53(6):1594–1600. doi: 10.1046/j.1523-1755.1998.00948.x. [DOI] [PubMed] [Google Scholar]
- Varanasi R., Bardeesy N., Ghahremani M., Petruzzi M. J., Nowak N., Adam M. A., Grundy P., Shows T. B., Pelletier J. Fine structure analysis of the WT1 gene in sporadic Wilms tumors. Proc Natl Acad Sci U S A. 1994 Apr 26;91(9):3554–3558. doi: 10.1073/pnas.91.9.3554. [DOI] [PMC free article] [PubMed] [Google Scholar]