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. 1990 Aug;34(8):1602–1604. doi: 10.1128/aac.34.8.1602

Comparison of ofloxacin, gentamicin, and tobramycin concentrations in tears and in vitro MICs for 90% of test organisms.

J Richman 1, H Zolezio 1, D Tang-Liu 1
PMCID: PMC171882  PMID: 2221871

Abstract

Concentrations of three anti-infective agents in tear film were monitored after one topical application in rabbits. Ofloxacin concentrations exceeded the MIC for 90% of the organisms tested (MIC90) (gram-negative and gram-positive organisms) for 240 min. Tobramycin concentrations exceeded the MIC90 for 10 min. Gentamicin concentrations exceeded the MIC90 for 20 min for gram-positive organisms and 120 min for gram-negative organisms.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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