Skip to main content
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 2001 Jul;85(1):73–78. doi: 10.1136/adc.85.1.73

Energy metabolism in relation to body composition and gender in adolescents

E G A H van Mil 1, K Westerterp 1, A Kester 1, W Saris 1
PMCID: PMC1718837  PMID: 11420210

Abstract

OBJECTIVE—To study the effect of body composition on average daily metabolic rate (ADMR) and basal metabolic rate (BMR) in adolescence, and to examine current BMR prediction equations.
STUDY—Dutch adolescents were pooled with previously reported American and British subjects (n = 90 overall). BMR and ADMR were analysed by multiple regression.
RESULTS—Fat-free mass, BMR, and ADMR were higher in the obese than in the non-obese group (mean (SD): 53.2 (10.7) kg, 8.35 (1.57) MJ/d, and 13.64 (2.78) MJ/d, compared with 41.0 (8.1) kg, 6.42(0.94) MJ/d, and 11.16 (2.21) MJ/d, respectively). BMR remained higher when adjusted for fat-free mass, age, and sex. ADMR adjusted for BMR was similar in the two groups. WHO equations overestimated BMR in obese boys and underestimated BMR in non-obese boys.
CONCLUSIONS—BMR, but not activity, is increased in obese adolescents and in male adolescents. The WHO BMR equations for adults are recommended for obese adolescents.



Full Text

The Full Text of this article is available as a PDF (137.3 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bandini L. G., Schoeller D. A., Dietz W. H. Energy expenditure in obese and nonobese adolescents. Pediatr Res. 1990 Feb;27(2):198–203. doi: 10.1203/00006450-199002000-00022. [DOI] [PubMed] [Google Scholar]
  2. Barlow S. E., Dietz W. H. Obesity evaluation and treatment: Expert Committee recommendations. The Maternal and Child Health Bureau, Health Resources and Services Administration and the Department of Health and Human Services. Pediatrics. 1998 Sep;102(3):E29–E29. doi: 10.1542/peds.102.3.e29. [DOI] [PubMed] [Google Scholar]
  3. Basdevant A., Boute D., Borys J. M. Who should be educated? Education strategies: could children educate their parents? Int J Obes Relat Metab Disord. 1999 May;23 (Suppl 4):S10–S13. doi: 10.1038/sj.ijo.0800914. [DOI] [PubMed] [Google Scholar]
  4. Boileau R. A., Lohman T. G., Slaughter M. H., Ball T. E., Going S. B., Hendrix M. K. Hydration of the fat-free body in children during maturation. Hum Biol. 1984 Dec;56(4):651–666. [PubMed] [Google Scholar]
  5. Bratteby L. E., Sandhagen B., Fan H., Enghardt H., Samuelson G. Total energy expenditure and physical activity as assessed by the doubly labeled water method in Swedish adolescents in whom energy intake was underestimated by 7-d diet records. Am J Clin Nutr. 1998 May;67(5):905–911. doi: 10.1093/ajcn/67.5.905. [DOI] [PubMed] [Google Scholar]
  6. Brown D. C., Kelnar C. J., Wu F. C. Energy metabolism during male human puberty. I. Changes in energy expenditure during the onset of puberty in boys. Ann Hum Biol. 1996 Jul-Aug;23(4):273–279. doi: 10.1080/03014469600004502. [DOI] [PubMed] [Google Scholar]
  7. Cheek D. B., Mellits D., Elliott D. Body water, height, and weight during growth in normal children. Am J Dis Child. 1966 Oct;112(4):312–317. doi: 10.1001/archpedi.1966.02090130086007. [DOI] [PubMed] [Google Scholar]
  8. Daniels S. R. Is there an epidemic of cardiovascular disease on the horizon? J Pediatr. 1999 Jun;134(6):665–666. doi: 10.1016/s0022-3476(99)70277-5. [DOI] [PubMed] [Google Scholar]
  9. Deurenberg P., Leenen R., Van der Kooy K., Hautvast J. G. In obese subjects the body fat percentage calculated with Siri's formula is an overestimation. Eur J Clin Nutr. 1989 Aug;43(8):569–575. [PubMed] [Google Scholar]
  10. DiPietro L., Mossberg H. O., Stunkard A. J. A 40-year history of overweight children in Stockholm: life-time overweight, morbidity, and mortality. Int J Obes Relat Metab Disord. 1994 Sep;18(9):585–590. [PubMed] [Google Scholar]
  11. Dietz W. H., Bandini L. G., Schoeller D. A. Estimates of metabolic rate in obese and nonobese adolescents. J Pediatr. 1991 Jan;118(1):146–149. doi: 10.1016/s0022-3476(05)81870-0. [DOI] [PubMed] [Google Scholar]
  12. Elliot D. L., Goldberg L., Kuehl K. S., Hanna C. Metabolic evaluation of obese and nonobese siblings. J Pediatr. 1989 Jun;114(6):957–962. doi: 10.1016/s0022-3476(89)80437-8. [DOI] [PubMed] [Google Scholar]
  13. Firouzbakhsh S., Mathis R. K., Dorchester W. L., Oseas R. S., Groncy P. K., Grant K. E., Finklestein J. Z. Measured resting energy expenditure in children. J Pediatr Gastroenterol Nutr. 1993 Feb;16(2):136–142. doi: 10.1097/00005176-199302000-00007. [DOI] [PubMed] [Google Scholar]
  14. Fomon S. J., Haschke F., Ziegler E. E., Nelson S. E. Body composition of reference children from birth to age 10 years. Am J Clin Nutr. 1982 May;35(5 Suppl):1169–1175. doi: 10.1093/ajcn/35.5.1169. [DOI] [PubMed] [Google Scholar]
  15. Freedman D. S., Dietz W. H., Srinivasan S. R., Berenson G. S. The relation of overweight to cardiovascular risk factors among children and adolescents: the Bogalusa Heart Study. Pediatrics. 1999 Jun;103(6 Pt 1):1175–1182. doi: 10.1542/peds.103.6.1175. [DOI] [PubMed] [Google Scholar]
  16. Goran M. I., Carpenter W. H., McGloin A., Johnson R., Hardin J. M., Weinsier R. L. Energy expenditure in children of lean and obese parents. Am J Physiol. 1995 May;268(5 Pt 1):E917–E924. doi: 10.1152/ajpendo.1995.268.5.E917. [DOI] [PubMed] [Google Scholar]
  17. Goran M. I., Carpenter W. H., Poehlman E. T. Total energy expenditure in 4- to 6-yr-old children. Am J Physiol. 1993 May;264(5 Pt 1):E706–E711. doi: 10.1152/ajpendo.1993.264.5.E706. [DOI] [PubMed] [Google Scholar]
  18. Goran M. I., Gower B. A., Nagy T. R., Johnson R. K. Developmental changes in energy expenditure and physical activity in children: evidence for a decline in physical activity in girls before puberty. Pediatrics. 1998 May;101(5):887–891. doi: 10.1542/peds.101.5.887. [DOI] [PubMed] [Google Scholar]
  19. Goran M. I. Variation in total energy expenditure in humans. Obes Res. 1995 Mar;3 (Suppl 1):59–66. doi: 10.1002/j.1550-8528.1995.tb00008.x. [DOI] [PubMed] [Google Scholar]
  20. Guo S. S., Roche A. F., Chumlea W. C., Gardner J. D., Siervogel R. M. The predictive value of childhood body mass index values for overweight at age 35 y. Am J Clin Nutr. 1994 Apr;59(4):810–819. doi: 10.1093/ajcn/59.4.810. [DOI] [PubMed] [Google Scholar]
  21. Halliday D., Hesp R., Stalley S. F., Warwick P., Altman D. G., Garrow J. S. Resting metabolic rate, weight, surface area and body composition in obese women. Int J Obes. 1979;3(1):1–6. [PubMed] [Google Scholar]
  22. Henry C. J., Dyer S., Ghusain-Choueiri A. New equations to estimate basal metabolic rate in children aged 10-15 years. Eur J Clin Nutr. 1999 Feb;53(2):134–142. doi: 10.1038/sj.ejcn.1600690. [DOI] [PubMed] [Google Scholar]
  23. Hergenroeder A. C., Klish W. J. Body composition in adolescent athletes. Pediatr Clin North Am. 1990 Oct;37(5):1057–1083. doi: 10.1016/s0031-3955(16)36975-9. [DOI] [PubMed] [Google Scholar]
  24. Hewitt M. J., Going S. B., Williams D. P., Lohman T. G. Hydration of the fat-free body mass in children and adults: implications for body composition assessment. Am J Physiol. 1993 Jul;265(1 Pt 1):E88–E95. doi: 10.1152/ajpendo.1993.265.1.E88. [DOI] [PubMed] [Google Scholar]
  25. Himes J. H., Dietz W. H. Guidelines for overweight in adolescent preventive services: recommendations from an expert committee. The Expert Committee on Clinical Guidelines for Overweight in Adolescent Preventive Services. Am J Clin Nutr. 1994 Feb;59(2):307–316. doi: 10.1093/ajcn/59.2.307. [DOI] [PubMed] [Google Scholar]
  26. Hoffmans M. D., Kromhout D., de Lezenne Coulander C. The impact of body mass index of 78,612 18-year old Dutch men on 32-year mortality from all causes. J Clin Epidemiol. 1988;41(8):749–756. doi: 10.1016/0895-4356(88)90161-8. [DOI] [PubMed] [Google Scholar]
  27. Holliday M. A. Metabolic rate and organ size during growth from infancy to maturity and during late gastation and early infancy. Pediatrics. 1971 Jan;47(1 Suppl):169+–169+. [PubMed] [Google Scholar]
  28. Katch V., Rocchini A., Becque D., Marks C., Moorehead K. Basal metabolism of obese adolescents: age, gender and body composition effects. Int J Obes. 1985;9(1):69–76. [PubMed] [Google Scholar]
  29. Livingstone M. B., Coward W. A., Prentice A. M., Davies P. S., Strain J. J., McKenna P. G., Mahoney C. A., White J. A., Stewart C. M., Kerr M. J. Daily energy expenditure in free-living children: comparison of heart-rate monitoring with the doubly labeled water (2H2(18)O) method. Am J Clin Nutr. 1992 Aug;56(2):343–352. doi: 10.1093/ajcn/56.2.343. [DOI] [PubMed] [Google Scholar]
  30. Lohman T. G. Skinfolds and body density and their relation to body fatness: a review. Hum Biol. 1981 May;53(2):181–225. [PubMed] [Google Scholar]
  31. Luepker R. V., Jacobs D. R., Prineas R. J., Sinaiko A. R. Secular trends of blood pressure and body size in a multi-ethnic adolescent population: 1986 to 1996. J Pediatr. 1999 Jun;134(6):668–674. doi: 10.1016/s0022-3476(99)70279-9. [DOI] [PubMed] [Google Scholar]
  32. Luke A., Schoeller D. A. Basal metabolic rate, fat-free mass, and body cell mass during energy restriction. Metabolism. 1992 Apr;41(4):450–456. doi: 10.1016/0026-0495(92)90083-m. [DOI] [PubMed] [Google Scholar]
  33. Molnár D. Estimates of metabolic rate in obese and nonobese adolescents. J Pediatr. 1992 Apr;120(4 Pt 1):660–661. doi: 10.1016/s0022-3476(05)82506-5. [DOI] [PubMed] [Google Scholar]
  34. Molnár D., Jeges S., Erhardt E., Schutz Y. Measured and predicted resting metabolic rate in obese and nonobese adolescents. J Pediatr. 1995 Oct;127(4):571–577. doi: 10.1016/s0022-3476(95)70114-1. [DOI] [PubMed] [Google Scholar]
  35. Molnár D., Schutz Y. Fat oxidation in nonobese and obese adolescents: effect of body composition and pubertal development. J Pediatr. 1998 Jan;132(1):98–104. doi: 10.1016/s0022-3476(98)70492-5. [DOI] [PubMed] [Google Scholar]
  36. Owens S., Gutin B., Ferguson M., Allison J., Karp W., Le N. A. Visceral adipose tissue and cardiovascular risk factors in obese children. J Pediatr. 1998 Jul;133(1):41–45. doi: 10.1016/s0022-3476(98)70175-1. [DOI] [PubMed] [Google Scholar]
  37. Poehlman E. T., Toth M. J., Webb G. D. Sodium-potassium pump activity contributes to the age-related decline in resting metabolic rate. J Clin Endocrinol Metab. 1993 Apr;76(4):1054–1057. doi: 10.1210/jcem.76.4.8386182. [DOI] [PubMed] [Google Scholar]
  38. Prentice A. M., Jebb S. A. Obesity in Britain: gluttony or sloth? BMJ. 1995 Aug 12;311(7002):437–439. doi: 10.1136/bmj.311.7002.437. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. Reilly J. J., Dorosty A. R., Emmett P. M. Prevalence of overweight and obesity in British children: cohort study. BMJ. 1999 Oct 16;319(7216):1039–1039. doi: 10.1136/bmj.319.7216.1039. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Seidell J. C. Obesity in Europe: scaling an epidemic. Int J Obes Relat Metab Disord. 1995 Sep;19 (Suppl 3):S1–S4. [PubMed] [Google Scholar]
  41. Simat B. M., Morley J. E., From A. H., Briggs J. E., Kaiser F. E., Levine A. S., Ahmed K. Variables affecting measurement of human red cell Na+,K+ATPase activity: technical factors, feeding, aging. Am J Clin Nutr. 1984 Aug;40(2):339–345. doi: 10.1093/ajcn/40.2.339. [DOI] [PubMed] [Google Scholar]
  42. Troiano R. P., Flegal K. M. Overweight children and adolescents: description, epidemiology, and demographics. Pediatrics. 1998 Mar;101(3 Pt 2):497–504. [PubMed] [Google Scholar]
  43. Westerterp K. R. Obesity and physical activity. Int J Obes Relat Metab Disord. 1999 Feb;23 (Suppl 1):59–64. doi: 10.1038/sj.ijo.0800797. [DOI] [PubMed] [Google Scholar]
  44. Westerterp K. R., Wouters L., van Marken Lichtenbelt W. D. The Maastricht protocol for the measurement of body composition and energy expenditure with labeled water. Obes Res. 1995 Mar;3 (Suppl 1):49–57. doi: 10.1002/j.1550-8528.1995.tb00007.x. [DOI] [PubMed] [Google Scholar]
  45. Whitaker R. C., Wright J. A., Pepe M. S., Seidel K. D., Dietz W. H. Predicting obesity in young adulthood from childhood and parental obesity. N Engl J Med. 1997 Sep 25;337(13):869–873. doi: 10.1056/NEJM199709253371301. [DOI] [PubMed] [Google Scholar]
  46. Wong W. W. Energy expenditure of female adolescents. J Am Coll Nutr. 1994 Aug;13(4):332–337. doi: 10.1080/07315724.1994.10718418. [DOI] [PubMed] [Google Scholar]
  47. van Mil E. A., Westerterp K. R., Gerver W. J., Curfs L. M., Schrander-Stumpel C. T., Kester A. D., Saris W. H. Energy expenditure at rest and during sleep in children with Prader-Willi syndrome is explained by body composition. Am J Clin Nutr. 2000 Mar;71(3):752–756. doi: 10.1093/ajcn/71.3.752. [DOI] [PubMed] [Google Scholar]
  48. van Mil E. G., Goris A. H., Westerterp K. R. Physical activity and the prevention of childhood obesity--Europe versus the United States. Int J Obes Relat Metab Disord. 1999 Apr;23 (Suppl 3):S41–S44. doi: 10.1038/sj.ijo.0800882. [DOI] [PubMed] [Google Scholar]
  49. van Mil E. G., Westerterp K. R., Kester A. D., Curfs L. M., Gerver W. J., Schrander-Stumpel C. T., Saris W. H. Activity related energy expenditure in children and adolescents with Prader-Willi syndrome. Int J Obes Relat Metab Disord. 2000 Apr;24(4):429–434. doi: 10.1038/sj.ijo.0801175. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES