Skip to main content
PMC home page
Archives of Disease in Childhood logoLink to Archives of Disease in Childhood
. 2001 Dec;85(6):463–468. doi: 10.1136/adc.85.6.463

Health care utilisation of infants with chronic lung disease, related to hospitalisation for RSV infection

A Greenough 1, S Cox 1, J Alexander 1, W Lenney 1, F Turnbull 1, S Burgess 1, P Chetcuti 1, N Shaw 1, A Woods 1, J Boorman 1, S Coles 1, J Turner 1, G RUSSELL 1
PMCID: PMC1719001  PMID: 11719328

Abstract

AIMS—To compare the use of health care resources and associated costs between infants with chronic lung disease (CLD) who had or had not an admission with a proven respiratory syncytial virus (RSV) infection.
METHODS—Review of community care, outpatient attendances, and readmissions in the first two years after birth. Patients: 235 infants (median gestational age 27 weeks) evaluated in four groups: 45infants with a proven RSV admission (RSV proven); 24 with a probable bronchiolitis admission; 60 with other respiratory admissions; and 106 with non-respiratory or no admissions.
RESULTS—The RSV proven compared to the other groups required more frequent and longer admissions to general paediatric wards and intensive care units, more outpatient attendances and GP consultations for respiratory related disorders, and had a higher total cost of care.
CONCLUSION—RSV hospitalisation in patients with CLD is associated with increased health service utilisation and costs in the first two years after birth.


Full Text

The Full Text of this article is available as a PDF (134.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boyce T. G., Mellen B. G., Mitchel E. F., Jr, Wright P. F., Griffin M. R. Rates of hospitalization for respiratory syncytial virus infection among children in medicaid. J Pediatr. 2000 Dec;137(6):865–870. doi: 10.1067/mpd.2000.110531. [DOI] [PubMed] [Google Scholar]
  2. Clark S. J., Beresford M. W., Subhedar N. V., Shaw N. J. Respiratory syncytial virus infection in high risk infants and the potential impact of prophylaxis in a United Kingdom cohort. Arch Dis Child. 2000 Oct;83(4):313–316. doi: 10.1136/adc.83.4.313. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Cunningham C. K., McMillan J. A., Gross S. J. Rehospitalization for respiratory illness in infants of less than 32 weeks' gestation. Pediatrics. 1991 Sep;88(3):527–532. [PubMed] [Google Scholar]
  4. Glezen W. P., Taber L. H., Frank A. L., Kasel J. A. Risk of primary infection and reinfection with respiratory syncytial virus. Am J Dis Child. 1986 Jun;140(6):543–546. doi: 10.1001/archpedi.1986.02140200053026. [DOI] [PubMed] [Google Scholar]
  5. Groothuis J. R., Gutierrez K. M., Lauer B. A. Respiratory syncytial virus infection in children with bronchopulmonary dysplasia. Pediatrics. 1988 Aug;82(2):199–203. [PubMed] [Google Scholar]
  6. Groothuis J. R., Salbenblatt C. K., Lauer B. A. Severe respiratory syncytial virus infection in older children. Am J Dis Child. 1990 Mar;144(3):346–348. doi: 10.1001/archpedi.1990.02150270096033. [DOI] [PubMed] [Google Scholar]
  7. Joffe S., Escobar G. J., Black S. B., Armstrong M. A., Lieu T. A. Rehospitalization for respiratory syncytial virus among premature infants. Pediatrics. 1999 Oct;104(4 Pt 1):894–899. doi: 10.1542/peds.104.4.894. [DOI] [PubMed] [Google Scholar]
  8. Kinali M., Greenough A., Dimitriou G., Yüksel B., Hooper R. Chronic respiratory morbidity following premature delivery--prediction by prolonged respiratory support requirement? Eur J Pediatr. 1999 Jun;158(6):493–496. doi: 10.1007/s004310051128. [DOI] [PubMed] [Google Scholar]
  9. Marchetti A., Lau H., Magar R., Wang L., Devercelli G. Impact of palivizumab on expected costs of respiratory syncytial virus infection in preterm infants: potential for savings. Clin Ther. 1999 Apr;21(4):752–766. doi: 10.1016/S0149-2918(00)88326-5. [DOI] [PubMed] [Google Scholar]
  10. Meissner H. C., Welliver R. C., Chartrand S. A., Fulton D. R., Rodriguez W. J., Groothuis J. R. Prevention of respiratory syncytial virus infection in high risk infants: consensus opinion on the role of immunoprophylaxis with respiratory syncytial virus hyperimmune globulin. Pediatr Infect Dis J. 1996 Dec;15(12):1059–1068. doi: 10.1097/00006454-199612000-00001. [DOI] [PubMed] [Google Scholar]
  11. Noble V., Murray M., Webb M. S., Alexander J., Swarbrick A. S., Milner A. D. Respiratory status and allergy nine to 10 years after acute bronchiolitis. Arch Dis Child. 1997 Apr;76(4):315–319. doi: 10.1136/adc.76.4.315. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Palta M., Sadek M., Barnet J. H., Evans M., Weinstein M. R., McGuinness G., Peters M. E., Gabbert D., Fryback D., Farrell P. Evaluation of criteria for chronic lung disease in surviving very low birth weight infants. Newborn Lung Project. J Pediatr. 1998 Jan;132(1):57–63. doi: 10.1016/s0022-3476(98)70485-8. [DOI] [PubMed] [Google Scholar]
  13. Prober C. G., Sullender W. M. Advances in prevention of respiratory syncytial virus infections. J Pediatr. 1999 Nov;135(5):546–558. doi: 10.1016/s0022-3476(99)70051-x. [DOI] [PubMed] [Google Scholar]
  14. Sharland M., Bedford-Russell A. Preventing respiratory syncitial virus bronchiolitis. BMJ. 2001 Jan 13;322(7278):62–63. doi: 10.1136/bmj.322.7278.62. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Sigurs N., Bjarnason R., Sigurbergsson F., Kjellman B. Respiratory syncytial virus bronchiolitis in infancy is an important risk factor for asthma and allergy at age 7. Am J Respir Crit Care Med. 2000 May;161(5):1501–1507. doi: 10.1164/ajrccm.161.5.9906076. [DOI] [PubMed] [Google Scholar]
  16. Stein R. T., Sherrill D., Morgan W. J., Holberg C. J., Halonen M., Taussig L. M., Wright A. L., Martinez F. D. Respiratory syncytial virus in early life and risk of wheeze and allergy by age 13 years. Lancet. 1999 Aug 14;354(9178):541–545. doi: 10.1016/S0140-6736(98)10321-5. [DOI] [PubMed] [Google Scholar]
  17. Thomas M., Bedford-Russell A., Sharland M. Hospitalisation for RSV infection in ex-preterm infants-implications for use of RSV immune globulin. Arch Dis Child. 2000 Aug;83(2):122–127. doi: 10.1136/adc.83.2.122. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Welliver R. C. Respiratory syncytial virus immunoglobulin and monoclonal antibodies in the prevention and treatment of respiratory syncytial virus infection. Semin Perinatol. 1998 Feb;22(1):87–95. doi: 10.1016/s0146-0005(98)80010-4. [DOI] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood are provided here courtesy of BMJ Publishing Group

RESOURCES