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. 1990 Oct;34(10):1865–1868. doi: 10.1128/aac.34.10.1865

Influence of growth rate on susceptibility to antimicrobial agents: biofilms, cell cycle, dormancy, and stringent response.

P Gilbert 1, P J Collier 1, M R Brown 1
PMCID: PMC171955  PMID: 2291653

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allison D. G., Evans D. J., Brown M. R., Gilbert P. Possible involvement of the division cycle in dispersal of Escherichia coli from biofilms. J Bacteriol. 1990 Mar;172(3):1667–1669. doi: 10.1128/jb.172.3.1667-1669.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brown M. R., Allison D. G., Gilbert P. Resistance of bacterial biofilms to antibiotics: a growth-rate related effect? J Antimicrob Chemother. 1988 Dec;22(6):777–780. doi: 10.1093/jac/22.6.777. [DOI] [PubMed] [Google Scholar]
  3. Brown M. R., Williams P. The influence of environment on envelope properties affecting survival of bacteria in infections. Annu Rev Microbiol. 1985;39:527–556. doi: 10.1146/annurev.mi.39.100185.002523. [DOI] [PubMed] [Google Scholar]
  4. Cooper S. A unifying model for the G1 period in prokaryotes and eukaryotes. Nature. 1979 Jul 5;280(5717):17–19. doi: 10.1038/280017a0. [DOI] [PubMed] [Google Scholar]
  5. Costerton J. W., Cheng K. J., Geesey G. G., Ladd T. I., Nickel J. C., Dasgupta M., Marrie T. J. Bacterial biofilms in nature and disease. Annu Rev Microbiol. 1987;41:435–464. doi: 10.1146/annurev.mi.41.100187.002251. [DOI] [PubMed] [Google Scholar]
  6. Cozens R. M., Markiewicz Z., Tuomanen E. Role of autolysins in the activities of imipenem and CGP 31608, a novel penem, against slowly growing bacteria. Antimicrob Agents Chemother. 1989 Oct;33(10):1819–1821. doi: 10.1128/aac.33.10.1819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Cozens R. M., Tuomanen E., Tosch W., Zak O., Suter J., Tomasz A. Evaluation of the bactericidal activity of beta-lactam antibiotics on slowly growing bacteria cultured in the chemostat. Antimicrob Agents Chemother. 1986 May;29(5):797–802. doi: 10.1128/aac.29.5.797. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Donachie W. D., Begg K. J. Growth of the bacterial cell. Nature. 1970 Sep 19;227(5264):1220–1224. doi: 10.1038/2271220a0. [DOI] [PubMed] [Google Scholar]
  9. Donachie W. D., Begg K. J., Vicente M. Cell length, cell growth and cell division. Nature. 1976 Nov 25;264(5584):328–333. doi: 10.1038/264328a0. [DOI] [PubMed] [Google Scholar]
  10. Evans D. J., Brown M. R., Allison D. G., Gilbert P. Susceptibility of bacterial biofilms to tobramycin: role of specific growth rate and phase in the division cycle. J Antimicrob Chemother. 1990 Apr;25(4):585–591. doi: 10.1093/jac/25.4.585. [DOI] [PubMed] [Google Scholar]
  11. Evans R. C., Holmes C. J. Effect of vancomycin hydrochloride on Staphylococcus epidermidis biofilm associated with silicone elastomer. Antimicrob Agents Chemother. 1987 Jun;31(6):889–894. doi: 10.1128/aac.31.6.889. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Gilbert P., Allison D. G., Evans D. J., Handley P. S., Brown M. R. Growth rate control of adherent bacterial populations. Appl Environ Microbiol. 1989 May;55(5):1308–1311. doi: 10.1128/aem.55.5.1308-1311.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Gristina A. G., Hobgood C. D., Webb L. X., Myrvik Q. N. Adhesive colonization of biomaterials and antibiotic resistance. Biomaterials. 1987 Nov;8(6):423–426. doi: 10.1016/0142-9612(87)90077-9. [DOI] [PubMed] [Google Scholar]
  14. Helmstetter C. E. DNA synthesis during the division cycle of rapidly growing Escherichia coli B/r. J Mol Biol. 1968 Feb 14;31(3):507–518. doi: 10.1016/0022-2836(68)90424-5. [DOI] [PubMed] [Google Scholar]
  15. Holmes C. J., Evans R. C. Resistance of bacterial biofilms to antibiotics. J Antimicrob Chemother. 1989 Jul;24(1):84–84. doi: 10.1093/jac/24.1.84. [DOI] [PubMed] [Google Scholar]
  16. Kjelleberg S., Humphrey B. A., Marshall K. C. Effect of interfaces on small, starved marine bacteria. Appl Environ Microbiol. 1982 May;43(5):1166–1172. doi: 10.1128/aem.43.5.1166-1172.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Koch A. L., Gross G. H. Growth conditions and rifampin susceptibility. Antimicrob Agents Chemother. 1979 Feb;15(2):220–228. doi: 10.1128/aac.15.2.220. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Matin A., Auger E. A., Blum P. H., Schultz J. E. Genetic basis of starvation survival in nondifferentiating bacteria. Annu Rev Microbiol. 1989;43:293–316. doi: 10.1146/annurev.mi.43.100189.001453. [DOI] [PubMed] [Google Scholar]
  19. Mitchison J. M. Enzyme synthesis in synchronous cultures. Science. 1969 Aug 15;165(3894):657–663. doi: 10.1126/science.165.3894.657. [DOI] [PubMed] [Google Scholar]
  20. Moyer C. L., Morita R. Y. Effect of growth rate and starvation-survival on the viability and stability of a psychrophilic marine bacterium. Appl Environ Microbiol. 1989 May;55(5):1122–1127. doi: 10.1128/aem.55.5.1122-1127.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Nickel J. C., Ruseska I., Wright J. B., Costerton J. W. Tobramycin resistance of Pseudomonas aeruginosa cells growing as a biofilm on urinary catheter material. Antimicrob Agents Chemother. 1985 Apr;27(4):619–624. doi: 10.1128/aac.27.4.619. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Novitsky J. A., Morita R. Y. Morphological characterization of small cells resulting from nutrient starvation of a psychrophilic marine vibrio. Appl Environ Microbiol. 1976 Oct;32(4):617–622. doi: 10.1128/aem.32.4.617-622.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Novitsky J. A., Morita R. Y. Survival of a psychrophilic marine Vibrio under long-term nutrient starvation. Appl Environ Microbiol. 1977 Mar;33(3):635–641. doi: 10.1128/aem.33.3.635-641.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
  24. Ochi K., Kandala J. C., Freese E. Initiation of Bacillus subtilis sporulation by the stringent response to partial amino acid deprivation. J Biol Chem. 1981 Jul 10;256(13):6866–6875. [PubMed] [Google Scholar]
  25. Ochi K., Ohsawa S. Initiation of antibiotic production by the stringent response of Bacillus subtilis Marburg. J Gen Microbiol. 1984 Oct;130(10):2473–2482. doi: 10.1099/00221287-130-10-2473. [DOI] [PubMed] [Google Scholar]
  26. Ochi K., Yamashita M. Indirect involvement of the stringent response of Bacillus subtilis in the development of self-resistance to its own antibiotic. J Antibiot (Tokyo) 1984 Sep;37(9):1085–1087. doi: 10.7164/antibiotics.37.1085. [DOI] [PubMed] [Google Scholar]
  27. Piggot P. J., Coote J. G. Genetic aspects of bacterial endospore formation. Bacteriol Rev. 1976 Dec;40(4):908–962. doi: 10.1128/br.40.4.908-962.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Prosser B. L., Taylor D., Dix B. A., Cleeland R. Method of evaluating effects of antibiotics on bacterial biofilm. Antimicrob Agents Chemother. 1987 Oct;31(10):1502–1506. doi: 10.1128/aac.31.10.1502. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Roszak D. B., Colwell R. R. Metabolic activity of bacterial cells enumerated by direct viable count. Appl Environ Microbiol. 1987 Dec;53(12):2889–2893. doi: 10.1128/aem.53.12.2889-2893.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Schaeffer P. Sporulation and the production of antibiotics, exoenzymes, and exotonins. Bacteriol Rev. 1969 Mar;33(1):48–71. doi: 10.1128/br.33.1.48-71.1969. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Stenström T. A., Conway P., Kjelleberg S. Inhibition by antibiotics of the bacterial response to long-term starvation of Salmonella typhimurium and the colon microbiota of mice. J Appl Bacteriol. 1989 Jul;67(1):53–59. doi: 10.1111/j.1365-2672.1989.tb04954.x. [DOI] [PubMed] [Google Scholar]
  32. Tuomanen E. Phenotypic tolerance: the search for beta-lactam antibiotics that kill nongrowing bacteria. Rev Infect Dis. 1986 Jul-Aug;8 (Suppl 3):S279–S291. doi: 10.1093/clinids/8.supplement_3.s279. [DOI] [PubMed] [Google Scholar]
  33. Tuomanen E., Tomasz A. Induction of autolysis in nongrowing Escherichia coli. J Bacteriol. 1986 Sep;167(3):1077–1080. doi: 10.1128/jb.167.3.1077-1080.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]

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