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Figure 1.
Electron micrograph of the renal biopsy showing membranous glomerulonephropathy. There is gross effacement of foot processes over thickened glomerular basement membranes. Numerous large electron dense subepithelial deposits are seen in the glomerular basement membranes, with basement membrane material seen between the deposits (stage 2) and focally fusing over the deposits (stage 3). In addition, some capillary loops show small subendothelial deposits. The mesangium shows moderate expansion with medium dense mesangial deposits.
Figure 2.
Histological examination of the liver biopsy showing mild to moderate lobular hepatitis with mild patchy piecemeal necrosis and minimal portal fibrosis (H&E stain; original magnification x120).
Figure 3.
Serial measurements showing normalisation of serum albumin concentration (solid line) and urinary albumin/creatinine ratio (dashed line) during treatment with lamivudine.