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. 1990 Dec;34(12):2426–2428. doi: 10.1128/aac.34.12.2426

Activity of cefixime against Helicobacter pylori and affinities for the penicillin-binding proteins.

F Ikeda 1, Y Yokota 1, Y Mine 1, M Tatsuta 1
PMCID: PMC172075  PMID: 2088199

Abstract

Cefixime induced the formation of rounded cells from the spiral bacillary form of Helicobacter pylori at the MIC or less. Three main penicillin-binding proteins, called A, B and C, were separated from H. pylori. Cefixime had the strongest affinity to penicillin-binding protein B. The binding of cefixime to this protein may induce the formation of rounded H. pylori cells.

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Selected References

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