Skip to main content
Archives of Disease in Childhood. Fetal and Neonatal Edition logoLink to Archives of Disease in Childhood. Fetal and Neonatal Edition
. 1998 Sep;79(2):F145–F147. doi: 10.1136/fn.79.2.f145

Brain imaging in neonatal hypoglycaemia

Z Traill, M Squier, P Anslow
PMCID: PMC1720833  PMID: 9828743

Abstract

Magnetic resonance imaging studies in two cases of neonatal hypoglycaemia showed cortical and white matter cerebral damage that was most obvious in the occipital lobes. Both cases showed oedema in the parieto-occipital cortex and underlying white matter in the acute phase, with profound atrophy of these regions in the chronic phase.
 These findings support those of pathological studies which suggest that hypoglycaemia induces cerebral damage by a mechanism separate from the effects of cerebral hypoxia-ischaemia caused by secondary seizures.



Full Text

The Full Text of this article is available as a PDF (101.0 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anderson J. M., Milner R. D., Strich S. J. Effects of neonatal hypoglycaemia on the nervous system: a pathological study. J Neurol Neurosurg Psychiatry. 1967 Aug;30(4):295–310. doi: 10.1136/jnnp.30.4.295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Auer R. N., Wieloch T., Olsson Y., Siesjö B. K. The distribution of hypoglycemic brain damage. Acta Neuropathol. 1984;64(3):177–191. doi: 10.1007/BF00688108. [DOI] [PubMed] [Google Scholar]
  3. Banker B. Q. The neuropathological effects of anoxia and hypoglycemia in the newborn. Dev Med Child Neurol. 1967 Oct;9(5):544–550. doi: 10.1111/j.1469-8749.1967.tb02323.x. [DOI] [PubMed] [Google Scholar]
  4. Barkovich A. J., Truwit C. L. Brain damage from perinatal asphyxia: correlation of MR findings with gestational age. AJNR Am J Neuroradiol. 1990 Nov-Dec;11(6):1087–1096. [PMC free article] [PubMed] [Google Scholar]
  5. Hirabayashi S., Kitahara T., Hishida T. Computed tomography in perinatal hypoxic and hypoglycemic encephalopathy with emphasis on follow-up studies. J Comput Assist Tomogr. 1980 Aug;4(4):451–456. doi: 10.1097/00004728-198008000-00006. [DOI] [PubMed] [Google Scholar]
  6. Spar J. A., Lewine J. D., Orrison W. W., Jr Neonatal hypoglycemia: CT and MR findings. AJNR Am J Neuroradiol. 1994 Sep;15(8):1477–1478. [PMC free article] [PubMed] [Google Scholar]

Articles from Archives of Disease in Childhood. Fetal and Neonatal Edition are provided here courtesy of BMJ Publishing Group

RESOURCES