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. 2002 Sep;87(2):F89–F93. doi: 10.1136/fn.87.2.F89

Measurement of right ventricular volume in healthy term and preterm neonates

S Clark, C Yoxall, N Subhedar
PMCID: PMC1721455  PMID: 12193512

Abstract

Background: Pulmonary hypertension is associated with worse perinatal outcomes in infants with respiratory disorders. In such infants right ventricular dysfunction may result in poor pulmonary blood flow.

Objective: To evaluate the practicability and repeatability of echocardiographic measurements of right ventricular volume in healthy term and preterm neonates, and to follow changes in right ventricular volume over the first 2 days of life.

Methods: Serial echocardiographic examinations were performed on day 0, 1, and 2 on healthy term and preterm neonates. Two methods of estimating right ventricular volume were assessed: the ellipsoid approximation and Simpson's stacked discs methods. Systolic and diastolic volumes on days 1 and 2 were compared with baseline values on day 0. Term and preterm volumes were compared at the same time points.

Results: Thirty five infants were recruited, 18 term and 17 preterm. Right ventricular volumes were significantly lower on day 1 and day 2 than baseline in both term and preterm infants. Median (interquartile range) end systolic and diastolic volumes for term infants on days 0, 1, and 2 were 1.04 (0.88–1.44), 0.82 (0.70–1.03), 0.92 (0.72–0.97) ml/kg and 2.21 (2.10–2.75), 2.05 (1.81–2.38), 1.91 (1.81–2.13) ml/kg respectively. In preterm infants the values were 1.09 (0.91–1.16), 0.72 (0.54–0.91), 0.61 (0.54–0.76) ml/kg and 2.09 (1.71–2.25), 1.47 (1.23–1.98), 1.43 (1.22–1.78) ml/kg respectively.

Conclusion: Right ventricular volume decreases over the first 2 days of life in healthy term and preterm infants.

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Figure 1 .

Figure 1

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An echocardiographic image of the right ventricle from the apical four chamber view, taken at end systole with the tricuspid valve closed. For the ellipsoid approximation method, the internal margin is traced using planimetry and the length of the ventricle is measured. For the Simpson's method the ventricle is sliced into 20 equal discs of known height and diameter.

Figure 2 .

Figure 2

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Change in right ventricular volumes over the first 2 days of life, showing medians and interquartile ranges, for (A) systole and (B) diastole.

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