Abstract
AIMS—Visual outcome of 66 eyes in 37 patients who had undergone treatment with either cryotherapy or diode laser for threshold retinopathy of prematurity was assessed. METHODS—17 patients, representing 30 eyes treated with cryotherapy, were examined at between 56 and 98 months corrected age (median 68 months). 20 patients representing 36 eyes treated with diode laser, were examined at between 30 and 66 months corrected age (median 51 months). Structural outcome was categorised as: optimal—flat posterior pole; suboptimal—macular ectopia, optic nerve hypoplasia, retinal fold involving the macula, and retinal detachment involving the macula. RESULTS—Optimal structural outcome was, in the absence of amblyopia, associated with optimal visual acuity (of 6/12 or better) in all cases, with most eyes achieving a visual acuity of 6/9 or 6/6. Suboptimal structural outcome was invariably associated with suboptimal visual acuity. Amblyopia was present in eight out of 20 cryotherapy treated eyes and in five out of 26 laser treated eyes with an optimal structural outcome. Refractive errors were significantly less in laser treated eyes as was the incidence of anisometropic amblyopia. CONCLUSION—Eyes treated with either cryotherapy or diode laser for threshold retinopathy of prematurity with optimal structural outcome are associated with development of optimal visual acuity—that is, 6/12 or better. Treatment with either cryotherapy or laser does not in itself reduce the visual potential of these eyes. Keywords: retinopathy of prematurity; cryotherapy; laser; visual acuity
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- Capone A., Jr, Diaz-Rohena R., Sternberg P., Jr, Mandell B., Lambert H. M., Lopez P. F. Diode-laser photocoagulation for zone 1 threshold retinopathy of prematurity. Am J Ophthalmol. 1993 Oct 15;116(4):444–450. doi: 10.1016/s0002-9394(14)71402-3. [DOI] [PubMed] [Google Scholar]
- Goggin M., O'Keefe M. Diode laser for retinopathy of prematurity--early outcome. Br J Ophthalmol. 1993 Sep;77(9):559–562. doi: 10.1136/bjo.77.9.559. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Knight-Nanan D. M., Algawi K., Bowell R., O'Keefe M. Advanced cicatricial retinopathy of prematurity--outcome and complications. Br J Ophthalmol. 1996 Apr;80(4):343–345. doi: 10.1136/bjo.80.4.343. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Knight-Nanan D. M., O'Keefe M. Refractive outcome in eyes with retinopathy of prematurity treated with cryotherapy or diode laser: 3 year follow up. Br J Ophthalmol. 1996 Nov;80(11):998–1001. doi: 10.1136/bjo.80.11.998. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Laws F., Laws D., Clark D. Cryotherapy and laser treatment for acute retinopathy of prematurity: refractive outcomes, a longitudinal study. Br J Ophthalmol. 1997 Jan;81(1):12–15. doi: 10.1136/bjo.81.1.12. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ling C. S., Fleck B. W., Wright E., Anderson C., Laing I. Diode laser treatment for retinopathy of prematurity: structural and functional outcome. Br J Ophthalmol. 1995 Jul;79(7):637–641. doi: 10.1136/bjo.79.7.637. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McNamara J. A., Tasman W., Vander J. F., Brown G. C. Diode laser photocoagulation for retinopathy of prematurity. Preliminary results. Arch Ophthalmol. 1992 Dec;110(12):1714–1716. doi: 10.1001/archopht.1992.01080240054029. [DOI] [PubMed] [Google Scholar]
- Reynolds J., Dobson V., Quinn G. E., Gilbert W. S., Tung B., Robertson J., Flynn J. T. Prediction of visual function in eyes with mild to moderate posterior pole residua of retinopathy of prematurity. Cryotherapy for Retinopathy of Prematurity Cooperative Group. Arch Ophthalmol. 1993 Aug;111(8):1050–1056. doi: 10.1001/archopht.1993.01090080046017. [DOI] [PubMed] [Google Scholar]
- White J. E., Repka M. X. Randomized comparison of diode laser photocoagulation versus cryotherapy for threshold retinopathy of prematurity: 3-year outcome. J Pediatr Ophthalmol Strabismus. 1997 Mar-Apr;34(2):83–122. doi: 10.3928/0191-3913-19970301-06. [DOI] [PubMed] [Google Scholar]