Skip to main content
The British Journal of Ophthalmology logoLink to The British Journal of Ophthalmology
. 2000 Jul;84(7):786–787. doi: 10.1136/bjo.84.7.786

Do sex and hormonal status influence choroidal circulation?

M Centofanti 1, S Bonini 1, G Manni 1, C Guinetti-Neuschul 1, M Bucci 1, A Harris 1
PMCID: PMC1723556  PMID: 10873995

Abstract

AIMS—To investigate the relation between pulse amplitude (PA), pulsatile ocular blood flow (POBF), and sex and hormonal status.
METHODS—Measurements of POBF and PA were obtained by ocular blood flow tonography in 76 healthy subjects: 32 males and 44 females (age range 17-77 years). Females were divided into two age groups: group 1 (premenopausal) 17-42 years, and group 2 (post-menopausal) 55 years old and over. Two groups of age matched males served as controls.
RESULTS—Premenopausal females demonstrated a significantly higher rate of POBF and PA than age matched males and post-menopausal females.
CONCLUSION—Sex and hormonal status were shown to influence choroidal circulation.



Full Text

The Full Text of this article is available as a PDF (87.2 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Belchetz P. E. Hormonal treatment of postmenopausal women. N Engl J Med. 1994 Apr 14;330(15):1062–1071. doi: 10.1056/NEJM199404143301508. [DOI] [PubMed] [Google Scholar]
  2. Belfort M. A., Saade G. R., Snabes M., Dunn R., Moise K. J., Jr, Cruz A., Young R. Hormonal status affects the reactivity of the cerebral vasculature. Am J Obstet Gynecol. 1995 Apr;172(4 Pt 1):1273–1278. doi: 10.1016/0002-9378(95)91492-7. [DOI] [PubMed] [Google Scholar]
  3. Fontana L., Poinoosawmy D., Bunce C. V., O'Brien C., Hitchings R. A. Pulsatile ocular blood flow investigation in asymmetric normal tension glaucoma and normal subjects. Br J Ophthalmol. 1998 Jul;82(7):731–736. doi: 10.1136/bjo.82.7.731. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Gisclard V., Miller V. M., Vanhoutte P. M. Effect of 17 beta-estradiol on endothelium-dependent responses in the rabbit. J Pharmacol Exp Ther. 1988 Jan;244(1):19–22. [PubMed] [Google Scholar]
  5. James C. B., Trew D. R., Clark K., Smith S. E. Factors influencing the ocular pulse--axial length. Graefes Arch Clin Exp Ophthalmol. 1991;229(4):341–344. doi: 10.1007/BF00170692. [DOI] [PubMed] [Google Scholar]
  6. Krakau C. E. Calculation of the pulsatile ocular blood flow. Invest Ophthalmol Vis Sci. 1992 Aug;33(9):2754–2756. [PubMed] [Google Scholar]
  7. Langham M. E., Farrell R. A., O'Brien V., Silver D. M., Schilder P. Blood flow in the human eye. Acta Ophthalmol Suppl. 1989;191:9–13. doi: 10.1111/j.1755-3768.1989.tb07080.x. [DOI] [PubMed] [Google Scholar]
  8. Langham M. E., Grebe R., Hopkins S., Marcus S., Sebag M. Choroidal blood flow in diabetic retinopathy. Exp Eye Res. 1991 Feb;52(2):167–173. doi: 10.1016/0014-4835(91)90256-e. [DOI] [PubMed] [Google Scholar]
  9. Langham M. E., Kramer T. Decreased choroidal blood flow associated with retinitis pigmentosa. Eye (Lond) 1990;4(Pt 2):374–381. doi: 10.1038/eye.1990.50. [DOI] [PubMed] [Google Scholar]
  10. Langham M. E., To'Mey K. F. A clinical procedure for the measurements of the ocular pulse-pressure relationship and the ophthalmic arterial pressure. Exp Eye Res. 1978 Jul;27(1):17–25. doi: 10.1016/0014-4835(78)90049-0. [DOI] [PubMed] [Google Scholar]
  11. Phillips C. I., Gore S. M. Ocular hypotensive effect of late pregnancy with and without high blood pressure. Br J Ophthalmol. 1985 Feb;69(2):117–119. doi: 10.1136/bjo.69.2.117. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. Ravalico G., Toffoli G., Pastori G., Crocè M., Calderini S. Age-related ocular blood flow changes. Invest Ophthalmol Vis Sci. 1996 Dec;37(13):2645–2650. [PubMed] [Google Scholar]
  13. Riva C. E., Grunwald J. E., Sinclair S. H., Petrig B. L. Blood velocity and volumetric flow rate in human retinal vessels. Invest Ophthalmol Vis Sci. 1985 Aug;26(8):1124–1132. [PubMed] [Google Scholar]
  14. St Louis P. J., Sulakhe P. V. Phosphorylation of cardiac sarcolemma by endogenous and exogenous protein kinases. Arch Biochem Biophys. 1979 Nov;198(1):227–240. doi: 10.1016/0003-9861(79)90414-4. [DOI] [PubMed] [Google Scholar]
  15. Trew D. R., James C. B., Thomas S. H., Sutton R., Smith S. E. Factors influencing the ocular pulse--the heart rate. Graefes Arch Clin Exp Ophthalmol. 1991;229(6):553–556. doi: 10.1007/BF00203321. [DOI] [PubMed] [Google Scholar]
  16. Trew D. R., Smith S. E. Postural studies in pulsatile ocular blood flow: I. Ocular hypertension and normotension. Br J Ophthalmol. 1991 Feb;75(2):66–70. doi: 10.1136/bjo.75.2.66. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from The British Journal of Ophthalmology are provided here courtesy of BMJ Publishing Group

RESOURCES