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. 2000 Sep;84(9):987–989. doi: 10.1136/bjo.84.9.987

Effect of cataract extraction and posterior chamber lens implantation on outflow facility and its response to pilocarpine in Korean subjects

C Kee 1, S Moon 1
PMCID: PMC1723623  PMID: 10966950

Abstract

AIM—To investigate the effect of the lens on outflow facility in Korean patients with cataracts.
METHODS—Intraocular pressure was measured by Goldmann applanation tonometry in 42 patients with cataracts and outflow facility was determined by tonography preoperatively, before and after instillation of pilocarpine. All patients received clear corneal phacoemulsification and silicone foldable intraocular lens implantation within the capsular bag by one surgeon. Two months after surgery, slit lamp examination and gonioscopy were performed and intraocular pressure and outflow facility were again determined. Statistical analysis was carried out using the Student's paired t test.
RESULTS—There were no anterior chamber reactions and no visible trabecular meshwork damage 2 months after surgery. Intraocular pressure 2 months after lens extraction decreased by a mean of 2.4 (SE 0.4) mm Hg (p<0.001) compared with the preoperative value; postoperative outflow facility with and without pilocarpine increased by 0.080 (0.019) µl/min/mm Hg (p<0.001) and 0.045 (0.014) µl/min/mm Hg (p<0.001), respectively, at 2 months compared with preoperative values. The facility response to pilocarpine after lens extraction, relative to the baseline value and preoperative response, increased by 10.7 (7.1)% which was not statistically significant (p>0.1).
CONCLUSION—Lens extraction causes a reduction in intraocular pressure and an increase in outflow facility in Korean subjects. Pilocarpine causes an increase in outflow facility which persists after cataract extraction and posterior chamber lens implantation.



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Selected References

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  1. ARMALY M. F., JEPSON N. C. Accommodation and the dynamics of the steady-state intraocular pressure. Invest Ophthalmol. 1962 Aug;1:480–483. [PubMed] [Google Scholar]
  2. Arciniegas A., Amaya L. E., Vicioso G. Mechanical behavior of the iris-lens-zonule-ciliary body system. Ophthalmologica. 1980;181(2):114–117. doi: 10.1159/000309036. [DOI] [PubMed] [Google Scholar]
  3. Crawford K., Terasawa E., Kaufman P. L. Reproducible stimulation of ciliary muscle contraction in the cynomolgus monkey via a permanent indwelling midbrain electrode. Brain Res. 1989 Dec 4;503(2):265–272. doi: 10.1016/0006-8993(89)91673-9. [DOI] [PubMed] [Google Scholar]
  4. GALIN M. A., BARAS I., PERRY R. Intraocular pressure following cataract extraction. Arch Ophthalmol. 1961 Jul;66:80–85. doi: 10.1001/archopht.1961.00960010082018. [DOI] [PubMed] [Google Scholar]
  5. Jahn C. E. Reduced intraocular pressure after phacoemulsification and posterior chamber intraocular lens implantation. J Cataract Refract Surg. 1997 Oct;23(8):1260–1264. doi: 10.1016/s0886-3350(97)80325-2. [DOI] [PubMed] [Google Scholar]
  6. Kaufman P. L., Bárány E. H. Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. Invest Ophthalmol. 1976 Oct;15(10):793–807. [PubMed] [Google Scholar]
  7. Kaufman P. L., Bárány E. H. Loss of acute pilocarpine effect on outflow facility following surgical disinsertion and retrodisplacement of the ciliary muscle from the scleral spur in the cynomolgus monkey. Invest Ophthalmol. 1976 Oct;15(10):793–807. [PubMed] [Google Scholar]
  8. LEE P. F., TROTTER R. R. Tonographic and gonioscopic studies before and after cataract extraction. AMA Arch Ophthalmol. 1957 Sep;58(3):407–416. doi: 10.1001/archopht.1957.00940010419015. [DOI] [PubMed] [Google Scholar]
  9. Meyer M. A., Savitt M. L., Kopitas E. The effect of phacoemulsification on aqueous outflow facility. Ophthalmology. 1997 Aug;104(8):1221–1227. doi: 10.1016/s0161-6420(97)30154-7. [DOI] [PubMed] [Google Scholar]
  10. Radius R. L., Schultz K., Sobocinski K., Schultz R. O., Easom H. Pseudophakia and intraocular pressure. Am J Ophthalmol. 1984 Jun;97(6):738–742. doi: 10.1016/0002-9394(84)90506-3. [DOI] [PubMed] [Google Scholar]
  11. Suzuki R., Tanaka K., Sagara T., Fujiwara N. Reduction of intraocular pressure after phacoemulsification and aspiration with intraocular lens implantation. Ophthalmologica. 1994;208(5):254–258. doi: 10.1159/000310502. [DOI] [PubMed] [Google Scholar]
  12. Tennen D. G., Masket S. Short-and long-term effect of clear corneal incisions on intraocular pressure. J Cataract Refract Surg. 1996 Jun;22(5):568–570. doi: 10.1016/s0886-3350(96)80010-1. [DOI] [PubMed] [Google Scholar]
  13. Van Buskirk E. M. Changes in the facility of aqueous outflow induced by lens depression and intraocular pressure in excised human eyes. Am J Ophthalmol. 1976 Nov;82(5):736–740. doi: 10.1016/0002-9394(76)90011-8. [DOI] [PubMed] [Google Scholar]
  14. Van Buskirk E. M., Grant W. M. Lens depression and aqueous outflow in enucleated primate eyes. Am J Ophthalmol. 1973 Nov;76(5):632–640. doi: 10.1016/0002-9394(73)90555-2. [DOI] [PubMed] [Google Scholar]

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