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. 2003 Dec;37(6):516–520. doi: 10.1136/bjsm.37.6.516

Effect of hyperbaric oxygen on oxygen uptake and measurements in the blood and tissues in a normobaric environment

A Hodges 1, J Delaney 1, J Lecomte 1, V Lacroix 1, D Montgomery 1
PMCID: PMC1724709  PMID: 14665591

Abstract

Objective: To examine venous partial pressure of oxygen (PvO2), transcutaneous oxygen tension (tcPO2), and VO2MAX in a normobaric environment after a single hyperbaric oxygen (HBO2) treatment.

Methods: This was a prospective study of conditions after the intervention compared with baseline. The participants were 10 moderately trained (VO2MAX = 57.6 ml/kg/min) men. Two HBO2 treatments consisting of breathing 95% oxygen at 2.5 atmospheres absolute (ATA) for 90 minutes were administered on non-consecutive days. Baseline testing included measures of VO2MAX, tcPO2, and anthropometry. At 6.0 (1.0) minutes after the first HBO2 treatment, a VO2MAX test was performed. After the second HBO2 treatment, leg and chest tcPO2 and PvO2 were monitored for 60 minutes.

Results: VO2MAX, running time, and peak blood lactate were not altered after the HBO2 treatment. Leg tcPO2 was lower (p = 0.003) and chest tcPO2 was unchanged after the HBO2 treatment compared with baseline values. PvO2 was significantly (p<0.001) lower in the first three minutes after treatment than subsequent values, but no other differences were found.

Conclusions: A single HBO2 treatment at 2.5 ATA for 90 minutes does not raise PvO2, tcPO2, or VO2MAX in a normobaric, normoxic environment.

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Selected References

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  1. Adams R. P., Welch H. G. Oxygen uptake, acid-base status, and performance with varied inspired oxygen fractions. J Appl Physiol Respir Environ Exerc Physiol. 1980 Nov;49(5):863–868. doi: 10.1152/jappl.1980.49.5.863. [DOI] [PubMed] [Google Scholar]
  2. Banister E. W., Taunton J. E., Patrick T., Oforsagd P., Duncan W. R. Effect of oxygen at high pressure at rest and during severe exercise. Respir Physiol. 1970 Jul;10(1):74–84. doi: 10.1016/0034-5687(70)90028-9. [DOI] [PubMed] [Google Scholar]
  3. Cabrić M., Medved R., Denoble P., Zivković M., Kovacević H. Effect of hyperbaric oxygenation on maximal aerobic performance in a normobaric environment. J Sports Med Phys Fitness. 1991 Sep;31(3):362–366. [PubMed] [Google Scholar]
  4. Cunningham D. A. Effects of breathing high concentrations of oxygen on treadmill performance. Res Q. 1966 Dec;37(4):491–494. [PubMed] [Google Scholar]
  5. Dooley J., King G., Slade B. Establishment of reference pressure of transcutaneous oxygen for the comparative evaluation of problem wounds. Undersea Hyperb Med. 1997 Winter;24(4):235–244. [PubMed] [Google Scholar]
  6. Ekblom B., Huot R., Stein E. M., Thorstensson A. T. Effect of changes in arterial oxygen content on circulation and physical performance. J Appl Physiol. 1975 Jul;39(1):71–75. doi: 10.1152/jappl.1975.39.1.71. [DOI] [PubMed] [Google Scholar]
  7. Huch A., Huch R., Hollmann G., Hockerts T., Keller H. P., Seiler D., Sadzek J., Lübbers D. W. Transcutaneous pO2 of volunteers during hyperbaric oxygenation. Biotelemetry. 1977;4(2):88–100. [PubMed] [Google Scholar]
  8. Jackson A. S., Pollock M. L. Generalized equations for predicting body density of men. Br J Nutr. 1978 Nov;40(3):497–504. doi: 10.1079/bjn19780152. [DOI] [PubMed] [Google Scholar]
  9. Kaijser L. Physical exercise under hyperbaric oxygen pressure. Life Sci. 1969 Sep 1;8(17):929–934. doi: 10.1016/0024-3205(69)90421-4. [DOI] [PubMed] [Google Scholar]
  10. Kelly D. L., Jr, Lassiter K. R., Vongsvivut A., Smith J. M. Effects of hyperbaric oxygenation and tissue oxygen studies in experimental paraplegia. J Neurosurg. 1972 Apr;36(4):425–429. doi: 10.3171/jns.1972.36.4.0425. [DOI] [PubMed] [Google Scholar]
  11. Knight D. R., Schaffartzik W., Poole D. C., Hogan M. C., Bebout D. E., Wagner P. D. Effects of hyperoxia on maximal leg O2 supply and utilization in men. J Appl Physiol (1985) 1993 Dec;75(6):2586–2594. doi: 10.1152/jappl.1993.75.6.2586. [DOI] [PubMed] [Google Scholar]
  12. Leach R. M., Rees P. J., Wilmshurst P. Hyperbaric oxygen therapy. BMJ. 1998 Oct 24;317(7166):1140–1143. doi: 10.1136/bmj.317.7166.1140. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. McGavock J. M., Lecomte J. L., Delaney J. S., Lacroix V. J., Hardy P., Montgomery D. L. Effects of hyperbaric oxygen on aerobic performance in a normobaric environment. Undersea Hyperb Med. 1999 Winter;26(4):219–224. [PubMed] [Google Scholar]
  14. Nielsen H. B., Madsen P., Svendsen L. B., Roach R. C., Secher N. H. The influence of PaO2, pH and SaO2 on maximal oxygen uptake. Acta Physiol Scand. 1998 Sep;164(1):89–87. doi: 10.1046/j.1365-201X.1998.00405.x. [DOI] [PubMed] [Google Scholar]
  15. Plewes J. L., Farhi L. E. Peripheral circulatory responses to acute hyperoxia. Undersea Biomed Res. 1983 Jun;10(2):123–129. [PubMed] [Google Scholar]
  16. Richardson R. S., Grassi B., Gavin T. P., Haseler L. J., Tagore K., Roca J., Wagner P. D. Evidence of O2 supply-dependent VO2 max in the exercise-trained human quadriceps. J Appl Physiol (1985) 1999 Mar;86(3):1048–1053. doi: 10.1152/jappl.1999.86.3.1048. [DOI] [PubMed] [Google Scholar]
  17. Robertson P. W., Hart B. B. Assessment of tissue oxygenation. Respir Care Clin N Am. 1999 Jun;5(2):221–263. [PubMed] [Google Scholar]
  18. Sheffield P. J. Measuring tissue oxygen tension: a review. Undersea Hyperb Med. 1998 Fall;25(3):179–188. [PubMed] [Google Scholar]
  19. Staples J. R., Clement D. B., Taunton J. E., McKenzie D. C. Effects of hyperbaric oxygen on a human model of injury. Am J Sports Med. 1999 Sep-Oct;27(5):600–605. doi: 10.1177/03635465990270050901. [DOI] [PubMed] [Google Scholar]
  20. Webster A. L., Syrotuik D. G., Bell G. J., Jones R. L., Bhambhani Y., Young M. Exercise after acute hyperbaric oxygenation: is there an ergogenic effect? Undersea Hyperb Med. 1998 Fall;25(3):153–159. [PubMed] [Google Scholar]
  21. Wilson G. D., Welch H. G. Effects of hyperoxic gas mixtures on exercise tolerance in man. Med Sci Sports. 1975 Spring;7(1):48–52. [PubMed] [Google Scholar]
  22. van der Kleij A. J., Kooyman R., Bakker D. J. Clinical value of transcutaneous PO2 assessment during hyperbaric oxygen therapy. Adv Exp Med Biol. 1997;411:113–120. doi: 10.1007/978-1-4615-5865-1_14. [DOI] [PubMed] [Google Scholar]

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