Abstract
This paper addresses six hallmark physiological requirements that must be correct if Hill's cardiovascular/ anaerobic/catastrophic model is the exclusive explanation for the fatigue that develops during maximum exercise to exhaustion. This leads to a review of the evidence supporting other, related "catastrophe" models that have been developed to explain fatigue during exercise of lower intensities and longer durations.
It is concluded that there is little published evidence supporting the theory that fatigue occurs only after physiological homeostasis fails according to the prediction of these catastrophe models. Rather, it is proposed that fatigue in any form of exercise may form part of a regulated, anticipatory response co-ordinated in the subconscious brain. The ultimate goal of this regulation is to preserve homeostasis in all physiological systems during exercise, regardless of intensity or duration or the environmental conditions in which it is undertaken.
Full Text
The Full Text of this article is available as a PDF (47.1 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Fitts R. H. Cellular mechanisms of muscle fatigue. Physiol Rev. 1994 Jan;74(1):49–94. doi: 10.1152/physrev.1994.74.1.49. [DOI] [PubMed] [Google Scholar]
- Fletcher W. M. Lactic acid in amphibian muscle. J Physiol. 1907 Mar 27;35(4):247–309. doi: 10.1113/jphysiol.1907.sp001194. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hill A. V. MUSCULAR ACTIVITY AND CARBOHYDRATE METABOLISM. Science. 1924 Dec 5;60(1562):505–514. doi: 10.1126/science.60.1562.505. [DOI] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
