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Emergency Medicine Journal : EMJ logoLink to Emergency Medicine Journal : EMJ
. 2002 Sep;19(5):405–407. doi: 10.1136/emj.19.5.405

A randomised, controlled trial comparing a tissue adhesive (2-octylcyanoacrylate) with adhesive strips (Steristrips) for paediatric laceration repair

A Mattick 1, G Clegg 1, T Beattie 1, T Ahmad 1
PMCID: PMC1725943  PMID: 12204985

Abstract

Objective: To compare the tissue adhesive 2-octylcyanoacrylate (Dermabond) with adhesive strips, Steristrips in paediatric laceration repair.

Method: Children with suitable lacerations were randomly allocated for wound closure with either a tissue adhesive or adhesive strips. Thirty children were treated in each group. Linear Visual Analogue Scores were used to judge parents' and nurses' opinions of the application of each treatment. A similar scoring system was used to judge the cosmetic outcome as viewed by parents and a plastic surgeon. Complications and trial failures were noted.

Results: Complete data were available for 44 of the children. Parents viewed the treatments as equally acceptable. In contrast those performing the procedure judged the tissue adhesive more difficult to apply. Scores of cosmetic outcome by both parents and the plastic surgeon showed no significant difference in the treatment method used. There were four children in the tissue adhesive group and one from the adhesive strip group in whom the wounds were unable to be closed.

Conclusion: Both tissue adhesives and adhesive strips are excellent "no needle" alternatives for the closure of suitable paediatric lacerations. This study suggests that the techniques are similar in efficacy, parental acceptability, and cosmetic outcome. The choice as to which is used may come down to economics and operator preference.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Barnett P., Jarman F. C., Goodge J., Silk G., Aickin R. Randomised trial of histoacryl blue tissue adhesive glue versus suturing in the repair of paediatric lacerations. J Paediatr Child Health. 1998 Dec;34(6):548–550. doi: 10.1046/j.1440-1754.1998.00300.x. [DOI] [PubMed] [Google Scholar]
  2. Bruns T. B., Robinson B. S., Smith R. J., Kile D. L., Davis T. P., Sullivan K. M., Quinn J. V. A new tissue adhesive for laceration repair in children. J Pediatr. 1998 Jun;132(6):1067–1070. doi: 10.1016/s0022-3476(98)70415-9. [DOI] [PubMed] [Google Scholar]
  3. Bruns T. B., Simon H. K., McLario D. J., Sullivan K. M., Wood R. J., Anand K. J. Laceration repair using a tissue adhesive in a children's emergency department. Pediatrics. 1996 Oct;98(4 Pt 1):673–675. [PubMed] [Google Scholar]
  4. Elmasalme F. N., Matbouli S. A., Zuberi M. S. Use of tissue adhesive in the closure of small incisions and lacerations. J Pediatr Surg. 1995 Jun;30(6):837–838. doi: 10.1016/0022-3468(95)90760-2. [DOI] [PubMed] [Google Scholar]
  5. Hollander J. E., Singer A. J. Application of tissue adhesives: rapid attainment of proficiency. Stony Brook Octylcyanoacrylate Study Group. Acad Emerg Med. 1998 Oct;5(10):1012–1017. doi: 10.1111/j.1553-2712.1998.tb02782.x. [DOI] [PubMed] [Google Scholar]
  6. Jackimczyk K., Pollack E. S. Management of pediatric wounds. Pediatr Ann. 1996 Aug;25(8):440–447. doi: 10.3928/0090-4481-19960801-07. [DOI] [PubMed] [Google Scholar]
  7. Liebelt E. L. Current concepts in laceration repair. Curr Opin Pediatr. 1997 Oct;9(5):459–464. doi: 10.1097/00008480-199710000-00002. [DOI] [PubMed] [Google Scholar]
  8. Messi G., Marchi A. G. Evaluation of skin laceration repair by tissue adhesive in the pediatric emergency room. Panminerva Med. 1992 Apr-Jun;34(2):77–80. [PubMed] [Google Scholar]
  9. Mizrahi S., Bickel A., Ben-Layish E. Use of tissue adhesives in the repair of lacerations in children. J Pediatr Surg. 1988 Apr;23(4):312–313. doi: 10.1016/s0022-3468(88)80195-7. [DOI] [PubMed] [Google Scholar]
  10. Osmond M. H., Klassen T. P., Quinn J. V. Economic comparison of a tissue adhesive and suturing in the repair of pediatric facial lacerations. J Pediatr. 1995 Jun;126(6):892–895. doi: 10.1016/s0022-3476(95)70203-2. [DOI] [PubMed] [Google Scholar]
  11. Osmond M. H. Pediatric wound management: the role of tissue adhesives. Pediatr Emerg Care. 1999 Apr;15(2):137–140. [PubMed] [Google Scholar]
  12. Osmond M. H., Quinn J. V., Sutcliffe T., Jarmuske M., Klassen T. P. A randomized, clinical trial comparing butylcyanoacrylate with octylcyanoacrylate in the management of selected pediatric facial lacerations. Acad Emerg Med. 1999 Mar;6(3):171–177. doi: 10.1111/j.1553-2712.1999.tb00151.x. [DOI] [PubMed] [Google Scholar]
  13. Penoff J. Skin closures using cyanoacrylate tissue adhesives. Plastic Surgery Educational Foundation DATA Committee. Device and Technique Assessment. Plast Reconstr Surg. 1999 Feb;103(2):730–731. doi: 10.1097/00006534-199902000-00061. [DOI] [PubMed] [Google Scholar]
  14. Quinn J. V., Drzewiecki A. E., Stiell I. G., Elmslie T. J. Appearance scales to measure cosmetic outcomes of healed lacerations. Am J Emerg Med. 1995 Mar;13(2):229–231. doi: 10.1016/0735-6757(95)90100-0. [DOI] [PubMed] [Google Scholar]
  15. Quinn J. V., Drzewiecki A., Li M. M., Stiell I. G., Sutcliffe T., Elmslie T. J., Wood W. E. A randomized, controlled trial comparing a tissue adhesive with suturing in the repair of pediatric facial lacerations. Ann Emerg Med. 1993 Jul;22(7):1130–1135. doi: 10.1016/s0196-0644(05)80977-1. [DOI] [PubMed] [Google Scholar]
  16. Quinn J., Wells G., Sutcliffe T., Jarmuske M., Maw J., Stiell I., Johns P. A randomized trial comparing octylcyanoacrylate tissue adhesive and sutures in the management of lacerations. JAMA. 1997 May 21;277(19):1527–1530. [PubMed] [Google Scholar]
  17. Saxena A. K., Willital G. H. Octylcyanoacrylate tissue adhesive in the repair of pediatric extremity lacerations. Am Surg. 1999 May;65(5):470–472. [PubMed] [Google Scholar]
  18. Sibert J. R., Maddocks G. B., Brown B. M. Childhood accidents--an endemic of epidemic proportion. Arch Dis Child. 1981 Mar;56(3):225–227. doi: 10.1136/adc.56.3.225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Simon H. K., McLario D. J., Bruns T. B., Zempsky W. T., Wood R. J., Sullivan K. M. Long-term appearance of lacerations repaired using a tissue adhesive. Pediatrics. 1997 Feb;99(2):193–195. doi: 10.1542/peds.99.2.193. [DOI] [PubMed] [Google Scholar]
  20. Singer A. J., Hollander J. E., Valentine S. M., Turque T. W., McCuskey C. F., Quinn J. V. Prospective, randomized, controlled trial of tissue adhesive (2-octylcyanoacrylate) vs standard wound closure techniques for laceration repair. Stony Brook Octylcyanoacrylate Study Group. Acad Emerg Med. 1998 Feb;5(2):94–99. doi: 10.1111/j.1553-2712.1998.tb02590.x. [DOI] [PubMed] [Google Scholar]
  21. Trott A. T. Cyanoacrylate tissue adhesives. An advance in wound care. JAMA. 1997 May 21;277(19):1559–1560. doi: 10.1001/jama.277.19.1559. [DOI] [PubMed] [Google Scholar]

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