Abstract
A tetracycline-resistant Haemophilus ducreyi strain isolated in the United States was shown to carry a 34-megadalton plasmid which hybridized with the 1.8-kilobase KpnI-HindIII Tet M probe. The complete Tn916 transposon hybridized with five different bands from this plasmid, suggesting homology throughout the length of the transposon.
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- Albritton W. L., Maclean I. W., Slaney L. A., Ronald A. R., Deneer H. G. Plasmid-mediated tetracycline resistance in Haemophilus ducreyi. Antimicrob Agents Chemother. 1984 Feb;25(2):187–190. doi: 10.1128/aac.25.2.187. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Brown J. T., Roberts M. C. Cloning and characterization of tetM gene from a Ureaplasma urealyticum strain. Antimicrob Agents Chemother. 1987 Nov;31(11):1852–1854. doi: 10.1128/aac.31.11.1852. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burdett V., Inamine J., Rajagopalan S. Heterogeneity of tetracycline resistance determinants in Streptococcus. J Bacteriol. 1982 Mar;149(3):995–1004. doi: 10.1128/jb.149.3.995-1004.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burdett V. Streptococcal tetracycline resistance mediated at the level of protein synthesis. J Bacteriol. 1986 Feb;165(2):564–569. doi: 10.1128/jb.165.2.564-569.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Clewell D. B., Gawron-Burke C. Conjugative transposons and the dissemination of antibiotic resistance in streptococci. Annu Rev Microbiol. 1986;40:635–659. doi: 10.1146/annurev.mi.40.100186.003223. [DOI] [PubMed] [Google Scholar]
- Deneer H. G., Slaney L., Maclean I. W., Albritton W. L. Mobilization of nonconjugative antibiotic resistance plasmids in Haemophilus ducreyi. J Bacteriol. 1982 Feb;149(2):726–732. doi: 10.1128/jb.149.2.726-732.1982. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elwell L. P., De Graaff J., Seibert D., Falkow S. Plasmid-linked ampicillin resistance in haempohilus influenza type b. Infect Immun. 1975 Aug;12(2):404–410. doi: 10.1128/iai.12.2.404-410.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Elwell L. P., Saunders J. R., Richmond M. H., Falkow S. Relationships among some R plasmids found in Haemophilus influenzae. J Bacteriol. 1977 Jul;131(1):356–362. doi: 10.1128/jb.131.1.356-362.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Gaillard J. L., Berche P., Sansonetti P. Transposon mutagenesis as a tool to study the role of hemolysin in the virulence of Listeria monocytogenes. Infect Immun. 1986 Apr;52(1):50–55. doi: 10.1128/iai.52.1.50-55.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Genco C. A., Knapp J. S., Clark V. L. Conjugation of plasmids of Neisseria gonorrhoeae to other Neisseria species: potential reservoirs for the beta-lactamase plasmid. J Infect Dis. 1984 Sep;150(3):397–401. doi: 10.1093/infdis/150.3.397. [DOI] [PubMed] [Google Scholar]
- Hächler H., Kayser F. H., Berger-Bächi B. Homology of a transferable tetracycline resistance determinant of Clostridium difficile with Streptococcus (Enterococcus) faecalis transposon Tn916. Antimicrob Agents Chemother. 1987 Jul;31(7):1033–1038. doi: 10.1128/aac.31.7.1033. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jones J. M., Yost S. C., Pattee P. A. Transfer of the conjugal tetracycline resistance transposon Tn916 from Streptococcus faecalis to Staphylococcus aureus and identification of some insertion sites in the staphylococcal chromosome. J Bacteriol. 1987 May;169(5):2121–2131. doi: 10.1128/jb.169.5.2121-2131.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Knapp J. S., Johnson S. R., Zenilman J. M., Roberts M. C., Morse S. A. High-level tetracycline resistance resulting from TetM in strains of Neisseria spp., Kingella denitrificans, and Eikenella corrodens. Antimicrob Agents Chemother. 1988 May;32(5):765–767. doi: 10.1128/aac.32.5.765. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Knapp J. S., Zenilman J. M., Biddle J. W., Perkins G. H., DeWitt W. E., Thomas M. L., Johnson S. R., Morse S. A. Frequency and distribution in the United States of strains of Neisseria gonorrhoeae with plasmid-mediated, high-level resistance to tetracycline. J Infect Dis. 1987 Apr;155(4):819–822. doi: 10.1093/infdis/155.4.819. [DOI] [PubMed] [Google Scholar]
- Levy S. B., Buu-Hoi A., Marshall B. Transposon Tn10-like tetracycline resistance determinants in Haemophilus parainfluenzae. J Bacteriol. 1984 Oct;160(1):87–94. doi: 10.1128/jb.160.1.87-94.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Marshall B., Roberts M., Smith A., Levy S. B. Homogeneity of transferable tetracycline-resistance determinants in Haemophilus species. J Infect Dis. 1984 Jun;149(6):1028–1029. doi: 10.1093/infdis/149.6.1028. [DOI] [PubMed] [Google Scholar]
- Morse S. A., Johnson S. R., Biddle J. W., Roberts M. C. High-level tetracycline resistance in Neisseria gonorrhoeae is result of acquisition of streptococcal tetM determinant. Antimicrob Agents Chemother. 1986 Nov;30(5):664–670. doi: 10.1128/aac.30.5.664. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Actis L. A., Crosa J. H. Molecular characterization of chloramphenicol-resistant Haemophilus parainfluenzae and Haemophilus ducreyi. Antimicrob Agents Chemother. 1985 Aug;28(2):176–180. doi: 10.1128/aac.28.2.176. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Hillier S. L., Hale J., Holmes K. K., Kenny G. E. Tetracycline resistance and tetM in pathogenic urogenital bacteria. Antimicrob Agents Chemother. 1986 Nov;30(5):810–812. doi: 10.1128/aac.30.5.810. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Kenny G. E. Conjugal transfer of transposon Tn916 from Streptococcus faecalis to Mycoplasma hominis. J Bacteriol. 1987 Aug;169(8):3836–3839. doi: 10.1128/jb.169.8.3836-3839.1987. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Knapp J. S. Host range of the conjugative 25.2-megadalton tetracycline resistance plasmid from Neisseria gonorrhoeae and related species. Antimicrob Agents Chemother. 1988 Apr;32(4):488–491. doi: 10.1128/aac.32.4.488. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Knapp J. S. Transfer of beta-lactamase plasmids from Neisseria gonorrhoeae to Neisseria meningitidis and commensal Neisseria species by the 25.2-megadalton conjugative plasmid. Antimicrob Agents Chemother. 1988 Sep;32(9):1430–1432. doi: 10.1128/aac.32.9.1430. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Koutsky L. A., Holmes K. K., LeBlanc D. J., Kenny G. E. Tetracycline-resistant Mycoplasma hominis strains contain streptococcal tetM sequences. Antimicrob Agents Chemother. 1985 Jul;28(1):141–143. doi: 10.1128/aac.28.1.141. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Moncla B. J. Tetracycline resistance and TetM in oral anaerobic bacteria and Neisseria perflava-N. sicca. Antimicrob Agents Chemother. 1988 Aug;32(8):1271–1273. doi: 10.1128/aac.32.8.1271. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M. C., Swenson C. D., Owens L. M., Smith A. L. Characterization of chloramphenicol-resistant Haemophilus influenzae. Antimicrob Agents Chemother. 1980 Oct;18(4):610–615. doi: 10.1128/aac.18.4.610. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M., Elwell L. P., Falkow S. Molecular characterization of two beta-lactamase-specifying plasmids isolated from Neisseria gonorrhoeae. J Bacteriol. 1977 Aug;131(2):557–563. doi: 10.1128/jb.131.2.557-563.1977. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts M., Falkow S. Conjugal transfer of R plasmids in Neisseria gonorrhoeae. Nature. 1977 Apr 14;266(5603):630–631. doi: 10.1038/266630a0. [DOI] [PubMed] [Google Scholar]
- Roberts M., Piot P., Falkow S. The ecology of gonococcal plasmids. J Gen Microbiol. 1979 Oct;114(2):491–494. doi: 10.1099/00221287-114-2-491. [DOI] [PubMed] [Google Scholar]
- Sanchez-Pescador R., Brown J. T., Roberts M., Urdea M. S. Homology of the TetM with translational elongation factors: implications for potential modes of tetM-conferred tetracycline resistance. Nucleic Acids Res. 1988 Feb 11;16(3):1218–1218. doi: 10.1093/nar/16.3.1218. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sanchez-Pescador R., Brown J. T., Roberts M., Urdea M. S. The nucleotide sequence of the tetracycline resistance determinant tetM from Ureaplasma urealyticum. Nucleic Acids Res. 1988 Feb 11;16(3):1216–1217. doi: 10.1093/nar/16.3.1216. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Van A. D., Bieth G., Bouanchaud D. H. Résistance plasmidique à la tétracycline chez Haemophilus influenzae. C R Acad Sci Hebd Seances Acad Sci D. 1975 Mar 10;280(10):1321–1323. [PubMed] [Google Scholar]
- Wray L. V., Jr, Jorgensen R. A., Reznikoff W. S. Identification of the tetracycline resistance promoter and repressor in transposon Tn10. J Bacteriol. 1981 Aug;147(2):297–304. doi: 10.1128/jb.147.2.297-304.1981. [DOI] [PMC free article] [PubMed] [Google Scholar]