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. 1989 Sep;33(9):1641–1644. doi: 10.1128/aac.33.9.1641

Inhibition of growth of the dimorphic fungus Paracoccidioides brasiliensis by ajoene.

G San-Blas 1, F San-Blas 1, F Gil 1, L Mariño 1, R Apitz-Castro 1
PMCID: PMC172723  PMID: 2817865

Abstract

Ajoene, a garlic-derived compound that prevents platelet activation, inhibited the growth of Paracoccidioides brasiliensis, a fungal pathogen for humans, by affecting the integrity of the fungal cytoplasmic membrane. This action may be the basis for the study of ajoene as a possible specific antifungal drug.

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Selected References

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