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Figure 1 .
Pedigree study of the donor family. The 18 year old donor was the proband case (II.4). The brother of the mother (I.1) is a homozygote and a non-identical twin. The mother (II.2) is a non-expressing homozygote and the brother of the proband (II.1) is a typical iron loaded homozygote. (Normal range ferritin 15-300 µg/l; TS, transferrin saturation, normal range 20-55%). C282Y refers to the characteristic mutation of the HFE gene.+/+, homozygote; +/−, heterozygote.
Selected References
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