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. 1989 Dec;33(12):2089–2091. doi: 10.1128/aac.33.12.2089

Microbial glycosylation of erythromycin A.

M S Kuo 1, D G Chirby 1, A D Argoudelis 1, J I Cialdella 1, J H Coats 1, V P Marshall 1
PMCID: PMC172826  PMID: 2619274

Abstract

Erythromycin A (compound 1) was inactivated by Streptomyces vendargensis ATCC 25507 in fermentation. The inactivation product was isolated and characterized by nuclear magnetic resonance and mass spectroscopy as 2'-(O-[beta-D-glucopyranosyl])erythromycin A (compound 2). The MICs of compounds 1 and 2 were determined. Compound 2 lacked antibiotic activity when tested against several gram-positive pathogens, as well as S. vendargensis.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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