Skip to main content
Heart logoLink to Heart
. 1998 Nov;80(5):447–452. doi: 10.1136/hrt.80.5.447

Secondary prevention in coronary heart disease: a randomised trial of nurse led clinics in primary care

N Campbell 1, L Ritchie 1, J Thain 1, H Deans 1, J Rawles 1, J Squair 1
PMCID: PMC1728827  PMID: 9930042

Abstract

Objective—To evaluate whether nurse run clinics in general practice improve secondary prevention in patients with coronary heart disease.
Design—Randomised controlled trial.
Setting—A random sample of 19 general practices in northeast Scotland.
Patients—1173 patients (685 men and 488 women) under 80 years with working diagnoses of coronary heart disease, but without terminal illness or dementia and not housebound.
Intervention—Nurse run clinics promoted medical and lifestyle aspects of secondary prevention and offered regular follow up.
Main outcome measures—Components of secondary prevention assessed at baseline and one year were: aspirin use; blood pressure management; lipid management; physical activity; dietary fat; and smoking status. A cumulative score was generated by counting the number of appropriate components of secondary prevention for each patient.
Results—There were significant improvements in aspirin management (odds ratio 3.22, 95% confidence interval 2.15 to 4.80), blood pressure management (5.32, 3.01 to 9.41), lipid management (3.19, 2.39 to 4.26), physical activity (1.67, 1.23 to 2.26) and diet (1.47, 1.10 to 1.96). There was no effect on smoking cessation (0.78, 0.47 to 1.28). Of six possible components of secondary prevention, the baseline mean was 3.27. The adjusted mean improvement attributable to intervention was 0.55 of a component (0.44 to 0.67). Improvement was found regardless of practice baseline performance.
Conclusions—Nurse run clinics proved practical to implement in general practice and effectively increased secondary prevention in coronary heart disease. Most patients gained at least one effective component of secondary prevention and, for them, future cardiovascular events and mortality could be reduced by up to a third.

 Keywords: coronary heart disease;  secondary prevention;  randomised controlled trial;  nurse led clinics

Full Text

The Full Text of this article is available as a PDF (125.2 KB).

Figure 1  .

Figure 1  

Selection of general practices and patients for the study.

Figure 2  .

Figure 2  

Trial profile.

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ashenden R., Silagy C., Weller D. A systematic review of the effectiveness of promoting lifestyle change in general practice. Fam Pract. 1997 Apr;14(2):160–176. doi: 10.1093/fampra/14.2.160. [DOI] [PubMed] [Google Scholar]
  2. Bain N. S., Foster K., Grimshaw J., MacLeod T. N., Broom J., Reid J., Ritchie L. D. Can audit of a local protocol for the management of lipid disorders effect and detect a change in clinical practice? Health Bull (Edinb) 1997 Mar;55(2):94–102. [PubMed] [Google Scholar]
  3. Browner W. S., Hulley S. B. Effect of risk status on treatment criteria. Implications of hypertension trials. Hypertension. 1989 May;13(5 Suppl):I51–I56. doi: 10.1161/01.hyp.13.5_suppl.i51. [DOI] [PubMed] [Google Scholar]
  4. Campbell N. C., Thain J., Deans H. G., Ritchie L. D., Rawles J. M. Secondary prevention in coronary heart disease: baseline survey of provision in general practice. BMJ. 1998 May 9;316(7142):1430–1434. doi: 10.1136/bmj.316.7142.1430. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Collins R., Peto R., MacMahon S., Hebert P., Fiebach N. H., Eberlein K. A., Godwin J., Qizilbash N., Taylor J. O., Hennekens C. H. Blood pressure, stroke, and coronary heart disease. Part 2, Short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context. Lancet. 1990 Apr 7;335(8693):827–838. doi: 10.1016/0140-6736(90)90944-z. [DOI] [PubMed] [Google Scholar]
  6. Cupples M. E., McKnight A. Randomised controlled trial of health promotion in general practice for patients at high cardiovascular risk. BMJ. 1994 Oct 15;309(6960):993–996. doi: 10.1136/bmj.309.6960.993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Daly L. E., Mulcahy R., Graham I. M., Hickey N. Long term effect on mortality of stopping smoking after unstable angina and myocardial infarction. Br Med J (Clin Res Ed) 1983 Jul 30;287(6388):324–326. doi: 10.1136/bmj.287.6388.324. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. McCartney P., Macdowall W., Thorogood M. A randomised controlled trial of feedback to general practitioners of their prophylactic aspirin prescribing. BMJ. 1997 Jul 5;315(7099):35–36. doi: 10.1136/bmj.315.7099.35. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Moher M., Schofield T., Weston S., Fullard E. Managing established coronary heart disease. BMJ. 1997 Jul 12;315(7100):69–70. doi: 10.1136/bmj.315.7100.69. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. O'Connor G. T., Buring J. E., Yusuf S., Goldhaber S. Z., Olmstead E. M., Paffenbarger R. S., Jr, Hennekens C. H. An overview of randomized trials of rehabilitation with exercise after myocardial infarction. Circulation. 1989 Aug;80(2):234–244. doi: 10.1161/01.cir.80.2.234. [DOI] [PubMed] [Google Scholar]
  11. Roe L., Strong C., Whiteside C., Neil A., Mant D. Dietary intervention in primary care: validity of the DINE method for diet assessment. Fam Pract. 1994 Dec;11(4):375–381. doi: 10.1093/fampra/11.4.375. [DOI] [PubMed] [Google Scholar]
  12. Sacks F. M., Pfeffer M. A., Moye L. A., Rouleau J. L., Rutherford J. D., Cole T. G., Brown L., Warnica J. W., Arnold J. M., Wun C. C. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. N Engl J Med. 1996 Oct 3;335(14):1001–1009. doi: 10.1056/NEJM199610033351401. [DOI] [PubMed] [Google Scholar]
  13. Sever P., Beevers G., Bulpitt C., Lever A., Ramsay L., Reid J., Swales J. Management guidelines in essential hypertension: report of the second working party of the British Hypertension Society. BMJ. 1993 Apr 10;306(6883):983–987. doi: 10.1136/bmj.306.6883.983. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Heart are provided here courtesy of BMJ Publishing Group

RESOURCES