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. 1999 Jun;81(6):618–620. doi: 10.1136/hrt.81.6.618

Pulmonary function and respiratory muscle strength in chronic heart failure: comparison between ischaemic and idiopathic dilated cardiomyopathy

M Daganou 1, I Dimopoulou 1, P Alivizatos 1, G Tzelepis 1
PMCID: PMC1729061  PMID: 10336921

Abstract

OBJECTIVE—To compare pulmonary function and respiratory muscle strength in patients with ischaemic and idiopathic dilated cardiomyopathy, well matched for indices of heart failure.
METHODS—The study involved 30 patients with ischaemic cardiomyopathy and 30 with idiopathic dilated cardiomyopathy. The groups were well matched for age, weight, and clinical severity of cardiac dysfunction as assessed by ejection fraction and the New York Heart Association functional class. There were more smokers in the ischaemic group (p < 0.05), but indices of pulmonary function were comparable.
RESULTS—Mean (SD) maximum static inspiratory pressure was lower in dilated cardiomyopathy than in ischaemic cardiomyopathy (73 (20) v 84 (22) cm H2O, p < 0.05), as was the maximum static expiratory pressure (90 (20) v 104 (21) cm H2O, p < 0.05).
CONCLUSIONS—For a given degree of cardiac dysfunction, the respiratory muscles are weaker in patients with idiopathic dilated cardiomyopathy than in those with ischaemic cardiomyopathy.


Keywords: respiratory muscles; congestive heart failure; pulmonary function; cardiomyopathy

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Selected References

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  1. Caforio A. L., Rossi B., Risaliti R., Siciliano G., Marchetti A., Angelini C., Crea F., Mariani M., Muratorio A. Type 1 fiber abnormalities in skeletal muscle of patients with hypertrophic and dilated cardiomyopathy: evidence of subclinical myogenic myopathy. J Am Coll Cardiol. 1989 Nov 15;14(6):1464–1473. doi: 10.1016/0735-1097(89)90383-5. [DOI] [PubMed] [Google Scholar]
  2. Chua T. P., Anker S. D., Harrington D., Coats A. J. Inspiratory muscle strength is a determinant of maximum oxygen consumption in chronic heart failure. Br Heart J. 1995 Oct;74(4):381–385. doi: 10.1136/hrt.74.4.381. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Dunnigan A., Staley N. A., Smith S. A., Pierpont M. E., Judd D., Benditt D. G., Benson D. W., Jr Cardiac and skeletal muscle abnormalities in cardiomyopathy: comparison of patients with ventricular tachycardia or congestive heart failure. J Am Coll Cardiol. 1987 Sep;10(3):608–618. doi: 10.1016/s0735-1097(87)80204-8. [DOI] [PubMed] [Google Scholar]
  4. Evans S. A., Watson L., Hawkins M., Cowley A. J., Johnston I. D., Kinnear W. J. Respiratory muscle strength in chronic heart failure. Thorax. 1995 Jun;50(6):625–628. doi: 10.1136/thx.50.6.625. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hammond M. D., Bauer K. A., Sharp J. T., Rocha R. D. Respiratory muscle strength in congestive heart failure. Chest. 1990 Nov;98(5):1091–1094. doi: 10.1378/chest.98.5.1091. [DOI] [PubMed] [Google Scholar]
  6. Lindsay D. C., Lovegrove C. A., Dunn M. J., Bennett J. G., Pepper J. R., Yacoub M. H., Poole-Wilson P. A. Histological abnormalities of muscle from limb, thorax and diaphragm in chronic heart failure. Eur Heart J. 1996 Aug;17(8):1239–1250. doi: 10.1093/oxfordjournals.eurheartj.a015042. [DOI] [PubMed] [Google Scholar]
  7. Mancini D. M., Henson D., La Manca J., Donchez L., Levine S. Benefit of selective respiratory muscle training on exercise capacity in patients with chronic congestive heart failure. Circulation. 1995 Jan 15;91(2):320–329. doi: 10.1161/01.cir.91.2.320. [DOI] [PubMed] [Google Scholar]
  8. Mancini D. M., Henson D., LaManca J., Levine S. Respiratory muscle function and dyspnea in patients with chronic congestive heart failure. Circulation. 1992 Sep;86(3):909–918. doi: 10.1161/01.cir.86.3.909. [DOI] [PubMed] [Google Scholar]
  9. McParland C., Krishnan B., Wang Y., Gallagher C. G. Inspiratory muscle weakness and dyspnea in chronic heart failure. Am Rev Respir Dis. 1992 Aug;146(2):467–472. doi: 10.1164/ajrccm/146.2.467. [DOI] [PubMed] [Google Scholar]
  10. McParland C., Resch E. F., Krishnan B., Wang Y., Cujec B., Gallagher C. G. Inspiratory muscle weakness in chronic heart failure: role of nutrition and electrolyte status and systemic myopathy. Am J Respir Crit Care Med. 1995 Apr;151(4):1101–1107. doi: 10.1164/ajrccm/151.4.1101. [DOI] [PubMed] [Google Scholar]
  11. Naum C. C., Sciurba F. C., Rogers R. M. Pulmonary function abnormalities in chronic severe cardiomyopathy preceding cardiac transplantation. Am Rev Respir Dis. 1992 Jun;145(6):1334–1338. doi: 10.1164/ajrccm/145.6.1334. [DOI] [PubMed] [Google Scholar]
  12. Nishimura Y., Maeda H., Tanaka K., Nakamura H., Hashimoto Y., Yokoyama M. Respiratory muscle strength and hemodynamics in chronic heart failure. Chest. 1994 Feb;105(2):355–359. doi: 10.1378/chest.105.2.355. [DOI] [PubMed] [Google Scholar]
  13. Shafig S. A., Sande M. A., Carruthers R. R., Killip T., Milhorat A. T. Skeletal muscle in idiopathic cardiomyopathy. J Neurol Sci. 1972 Mar;15(3):303–320. doi: 10.1016/0022-510x(72)90072-x. [DOI] [PubMed] [Google Scholar]
  14. Stassijns G., Lysens R., Decramer M. Peripheral and respiratory muscles in chronic heart failure. Eur Respir J. 1996 Oct;9(10):2161–2167. doi: 10.1183/09031936.96.09102161. [DOI] [PubMed] [Google Scholar]
  15. Wilson J. R., Mancini D. M., McCully K., Ferraro N., Lanoce V., Chance B. Noninvasive detection of skeletal muscle underperfusion with near-infrared spectroscopy in patients with heart failure. Circulation. 1989 Dec;80(6):1668–1674. doi: 10.1161/01.cir.80.6.1668. [DOI] [PubMed] [Google Scholar]

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